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Synthesis, characterization and bioactivity investigation of bioglass/hydroxyapatite composite

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TLDR
In this article, a composite sample of hydroxyapatite with synthesized bioglass was prepared at 1000°C and characterized by X-ray powder diffraction (XRD) and surface electron microscopy (SEM).
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This article is published in Ceramics International.The article was published on 2010-01-01. It has received 162 citations till now. The article focuses on the topics: Simulated body fluid & Bioactive glass.

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Journal ArticleDOI

Bioactive Glass and Glass-Ceramic Scaffolds for Bone Tissue Engineering

TL;DR: Current knowledge on porous bone tissue engineering scaffolds on the basis of melt-derived bioactive silicate glass compositions and relevant composite structures is reviewed and discussed.
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Thermogelling chitosan-collagen-bioactive glass nanoparticle hybrids as potential injectable systems for tissue engineering.

TL;DR: It can be stated that innovative composites were successfully designed and synthesized in this research with promising potential to be used as thermoresponsive biomaterials for bone-tissue bioapplications.
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Synthesis of silicon-substituted hydroxyapatite by a hydrothermal method with two different phosphorous sources

TL;DR: Silicon-substituted hydroxyapatite (Si-HA) with up to 1.8% Si content was prepared successfully by a hydrothermal method, using Ca(NO3)2, (NH4)3PO4 or Si(OCH2CH3)4 (TEOS) as starting materials.
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Hydroxyapatite and tricalcium phosphate composites with bioactive glass as second phase: State of the art and current applications.

TL;DR: The state of the art and current applications of composites, based on HA or TCP with bioactive glass as second phase, are presented and discussed and a special emphasis is given to the processing and mechanical behaviour of these systems, together with their biological implications, as a function of the composition of the glass employed as secondphase.
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Hydrogel/bioactive glass composites for bone regeneration applications: synthesis and characterisation.

TL;DR: The combination of enhanced mechanical properties and the deposition of apatite on the surface of these hydrogel based composites make them an ideal candidate as bone graft substitutes in cancellous bone defects or low load bearing applications.
References
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Journal ArticleDOI

Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W.

TL;DR: The results support the concept that the apatite phase on the surface of glass-ceramic A-W is formed by a chemical reaction of the glass- Aceramic with the Ca2+, HPO4(2-), and OH- ions in the body fluid.
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The story of Bioglass

TL;DR: The 40 year history of the development of bioactive glasses is reviewed, with emphasis on the first composition, 45S5 Bioglass®, that has been in clinical use since 1985, and the steps of discovery, characterization, in vivo and in vitro evaluation, clinical studies and product development are summarized along with the technology transfer processes.
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Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass 45S5 dissolution.

TL;DR: The identification of differentially expressed genes by cDNA microarray analysis has offered new insights into the mode of action of bioactive glasses and has proven to be an effective tool in evaluating their osteoproductive properties.
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Calcium phosphates as substitution of bone tissues

TL;DR: In this paper, a review of the role played by biological calcium phosphates in bone regeneration is presented, where the synthesis procedures to obtain in the laboratory calcium deficient carbonate nanoapatite both in bulk and thin film forms, as well as the characterization methods applied to these materials are described.
Journal ArticleDOI

Chemical characterization of silicon-substituted hydroxyapatite.

TL;DR: Chemical analysis confirmed the proposed substitution of the silicon (or silicate) ion for the phosphorus (or phosphate) ion in hydroxyapatite and demonstrated that phase-pure silicon-substituted hydroxyAPatite may be prepared using a simple precipitation technique.
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