TAS2R38 (phenylthiocarbamide) haplotypes, coronary heart disease traits, and eating behavior in the British Women's Heart and Health Study
Nic Timpson,Mikkel B. Christensen,Debbie A Lawlor,Tom R. Gaunt,Ian N.M. Day,Shah Ebrahim,George Davey Smith +6 more
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TAS2R38 status was not an important determinant of CHD, related risk factors, or eating behavior in the British Women's Heart and Health Study sample.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2005-05-01 and is currently open access. It has received 93 citations till now. The article focuses on the topics: Odds ratio & Body mass index.read more
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The human obesity gene map: the 2005 update.
Tuomo Rankinen,Aamir Zuberi,Yvon C. Chagnon,S. John Weisnagel,George Argyropoulos,Brandon Walts,Louis Pérusse,Claude Bouchard +7 more
TL;DR: The 12th update of the human obesity gene map is presented, which incorporates published results up to the end of October 2005, and shows putative loci on all chromosomes except Y.
Journal ArticleDOI
The human obesity gene map: the 2004 update.
Louis Pérusse,Tuomo Rankinen,Aamir Zuberi,Yvon C. Chagnon,S. John Weisnagel,George Argyropoulos,Brandon Walts,Eric E. Snyder,Claude Bouchard +8 more
TL;DR: This paper presents the 12th update of the human obesity gene map, which incorporates published results up to the end of October 2005, and shows putative loci on all chromosomes except Y.
Journal ArticleDOI
Nutritional Implications of Genetic Taste Variation: The Role of PROP Sensitivity and Other Taste Phenotypes
TL;DR: The primary goal of this review is to assess the current understanding of the role of the PROP bitter taste phenotype in food selection and body weight in both children and adults.
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Genetic Variation in Taste and Its Influence on Food Selection
TL;DR: The present state of knowledge of the genetic variation in taste is summarized, and how such variation might influence food intake behaviors is summarized.
Journal ArticleDOI
Taste and weight: is there a link?
TL;DR: Current understanding of the relations between the ability to taste different tastes (ie, taste threshold for sweet, bitter, sour, salt, and umami) and body mass and body weight is reviewed.
References
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Homeostasis model assessment : insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
TL;DR: The correlation of the model's estimates with patient data accords with the hypothesis that basal glucose and insulin interactions are largely determined by a simple feed back loop.
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A simple salting out procedure for extracting DNA from human nucleated cells
TL;DR: A rapid, safe and inexpensive method was developed to simplify the deprotein-ization procedure that yielded quantities comparable to those obtained from phenol-chloroform extractions, rendering the entire process of RFLP analysis free of toxic materials.
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A new statistical method for haplotype reconstruction from population data.
TL;DR: A new statistical method is presented, applicable to genotype data at linked loci from a population sample, that improves substantially on current algorithms and performs well in absolute terms, suggesting that reconstructing haplotypes experimentally or by genotyping additional family members may be an inefficient use of resources.
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‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?
George Davey Smith,Shah Ebrahim +1 more
TL;DR: Mendelian randomization provides new opportunities to test causality and demonstrates how investment in the human genome project may contribute to understanding and preventing the adverse effects on human health of modifiable exposures.
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A Comparison of Bayesian Methods for Haplotype Reconstruction from Population Genotype Data
Matthew Stephens,Peter Donnelly +1 more
TL;DR: A new algorithm is introduced that combines the modeling strategy of one method with the computational strategies of another and outperforms all three existing methods for inferring haplotypes from genotype data in a population sample.