Temperature and host defense.
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This article is published in Microbiological Research.The article was published on 1979-06-01 and is currently open access. It has received 142 citations till now.read more
Citations
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Journal ArticleDOI
The Clinical Significance of Positive Blood Cultures: A Comprehensive Analysis of 500 Episodes of Bacteremia and Fungemia in Adults. II. Clinical Observations, with Special Reference to Factors Influencing Prognosis
TL;DR: Although some adverse prognostic factors are not amenable to intervention, prevention of nosocomial bacteremia and fungemia and early reversal of hypotension may reduce the death rate from sepsis.
Journal ArticleDOI
New Concepts on the Pathogenesis of Fever
TL;DR: Investigators trying to determine what triggers the hypothalamus to initiate fever in a particular disease must now consider these three endogenous pyrogens, either alone or together, as mediators of fever.
Journal Article
Stress and immune function: a bibliographic review.
TL;DR: This paper identifies eight stressors that typically occur in modern livestock production units: heat, cold, crowding, mixing, weaning, limit-feeding, noise and restraint, all of which have been shown to alter the immune system of animals.
Journal ArticleDOI
Fever: causes and consequences.
TL;DR: The present review examines fever-resistance in neonates, the blunting of fever in the aged, and the behaviorally induced rise in body temperature following infection in ectotherms, and takes up the question of whether fever enhances immune responsiveness, and through such enhancement contributes to host survival.
References
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Fever of unexplained origin: report on 100 cases.
Journal ArticleDOI
Cellular responses to combinations of hyperthermia and radiation.
TL;DR: The two principal rationales for applying hyperthermia in cancer therapy are that: the S phase, which is relatively radioresistant, is the most sensitive phase tohyperthermia, and can be selectively radiosensitized by combining hyperThermia with x-irradiation, and the cycling tumor cells in S phase could be killed by subjecting these cells toHyperthermia.
Journal ArticleDOI
Selective heat sensitivity of cancer cells. Biochemical and clinical studies.
Renato Cavaliere,Enrico C. Ciocatto,Beppino C. Giovanella,Charles Heidelberger,Robert O. Johnson,Mario Margottini,Bruno Mondovi,Guido Moricca,A. Rossi-Fanelli +8 more
TL;DR: No conclusions about survivals can be drawn at present although four of seven patients with malignant melanomas treated only by heat perfusion are alive and well with functional limbs 28, 27, 11 and 7 months after treatment.
Journal ArticleDOI
Variation in Sensitivity to Heat Shock during the Cell-cycle of Chinese Hamster Cells in Vitro
Arthur Westra,W.C. Dewey +1 more
TL;DR: Heating of synchronous cells, obtained by the selective removal of mitotic cells from an asynchronous population, revealed that the mitotic and S phases were the most sensitive, primarily indicated by the smaller shoulders on the survival curves compared with the curve for cells heated in the resistant G1 phase.
Related Papers (5)
Hyperthermia and human leukocyte functions: effects on response of lymphocytes to mitogen and antigen and bactericidal capacity of monocytes and neutrophils.
N J Roberts,R T Steigbigel +1 more