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The Carbohydrates: Chemistry and Biochemistry
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The article was published on 1970-11-01 and is currently open access. It has received 399 citations till now.read more
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Journal ArticleDOI
Acrylamide from Maillard reaction products
Richard H. Stadler,Imre Blank,Natalia Varga,Fabien Robert,Jörg Hau,Philippe A. Guy,Marie-Claude Robert,Sonja Riediker +7 more
TL;DR: It is shown that acrylamide can be released by the thermal treatment of certain amino acids (asparagine, for example), particularly in combination with reducing sugars, and of early Maillard reaction products (N-glycosides).
Journal ArticleDOI
Lyophilization and development of solid protein pharmaceuticals
TL;DR: Four interrelated topics are discussed: lyophilization and its denaturation stresses, cryo- and lyo-protection of proteins by excipients, design of a robust lyophILization cycle, and with emphasis, instability, stabilization, and formulation of solid protein pharmaceuticals.
Journal ArticleDOI
Protein glycation, diabetes, and aging.
Peter C. Ulrich,Anthony Cerami +1 more
TL;DR: A new class of agents, exemplified by 4,5-dimethyl-3-phenacylthiazolium chloride (DPTC), which can chemically break already-formed AGE protein-protein crosslinks, are developed, based on a new theory of AGE crosslinking that postulates that alpha-dicarbonyl structures are present in AGEprotein- protein crosslinks.
Book ChapterDOI
Anomeric-oxygen activation for glycoside synthesis: the trichloroacetimidate method.
Richard R. Schmidt,Willy Kinzy +1 more
Book ChapterDOI
Microorganisms and enzymes involved in the degradation of plant fiber cell walls
TL;DR: This chapter describes the structure of wood and the main wood components, cellulose, hemicelluloses and lignins and the enzyme and enzyme mechanisms used by fungi and bacteria to modify and degrade these components are described in detail.