The Central Sensitization Inventory (CSI): Establishing Clinically Significant Values for Identifying Central Sensitivity Syndromes in an Outpatient Chronic Pain Sample
Randy Neblett,Howard Cohen,YunHee Choi,Meredith M. Hartzell,Mark R. Williams,Tom G. Mayer,Robert J. Gatchel +6 more
TLDR
The CSI is a new self-report screening instrument to help identify patients with CSSs, including fibromyalgia, and a normative nonclinical sample to determine a clinically relevant cutoff value is investigated.About:
This article is published in The Journal of Pain.The article was published on 2013-05-01 and is currently open access. It has received 427 citations till now. The article focuses on the topics: Population & Fibromyalgia.read more
Citations
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Neuropathic Pain: Central vs. Peripheral Mechanisms
TL;DR: Evidence is sought for PNS and CNS independently generating neuropathic pain signals and the possibility of standalone central contributions to pNP may be assisted by a reconsideration of the agreed terms or criteria for diagnosing the presence of central sensitization.
Journal ArticleDOI
Applying modern pain neuroscience in clinical practice: criteria for the classification of central sensitization pain.
Jo Nijs,Rafael Torres-Cueco,C. Paul van Wilgen,Enrique Lluch Girbés,Filip Struyf,Nathalie Roussel,Nathalie Roussel,Jessica Van Oosterwijck,Jessica Van Oosterwijck,Liesbeth Daenen,Liesbeth Daenen,Kevin Kuppens,Kevin Kuppens,Luc Vanderweeën,Linda Hermans,David Beckwée,Lennard Voogt,Lennard Voogt,Jacqui Clark,Niamh Moloney,Niamh Moloney,Mira Meeus,Mira Meeus +22 more
TL;DR: Clinicians can use the proposed classification algorithm for differentiating neuropathic, nociceptive, and central sensitization pain for each individual patient with chronic pain.
Journal ArticleDOI
Toward a Mechanism-Based Approach to Pain Diagnosis
TL;DR: How identifying the specific mechanisms that operate in the nervous system to produce chronic pain in individual patients could provide the basis for a targeted and rational precision medicine approach to controlling pain is discussed, using chronic low back pain as an example.
Journal ArticleDOI
Low back pain: guidelines for the clinical classification of predominant neuropathic, nociceptive, or central sensitization pain.
Jo Nijs,Adri Apeldoorn,H. J. M. Hallegraeff,Jacqui Clark,Rob J. E. M. Smeets,Anneleen Malfliet,Enrique Lluch Girbés,Enrique Lluch Girbés,Margot De Kooning,Margot De Kooning,Kelly Ickmans +10 more
TL;DR: The pain classification system for L BP should be an addition to available classification systems and diagnostic procedures for LBP, as it is focussed on pain mechanisms solely.
Journal ArticleDOI
Effect of pain neuroscience education combined with cognition-targeted motor control training on chronic spinal pain: a randomized clinical trial
Anneleen Malfliet,Jeroen Kregel,Iris Coppieters,Robby De Pauw,Mira Meeus,Mira Meeus,Nathalie Roussel,Barbara Cagnie,Lieven Danneels,Jo Nijs +9 more
TL;DR: Pain neuroscience education combined with cognition-targeted motor control training appears to be more effective than current best-evidence physiotherapy for improving pain, symptoms of central sensitization, disability, mental and physical functioning, and pain cognitions in individuals with chronic spinal pain.
References
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Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine.
Mark H. Zweig,Gregory Campbell +1 more
TL;DR: Receiver-operating characteristic (ROC) plots provide a pure index of accuracy by demonstrating the limits of a test's ability to discriminate between alternative states of health over the complete spectrum of operating conditions.
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Central sensitization: implications for the diagnosis and treatment of pain.
TL;DR: Diagnostic criteria to establish the presence of central sensitization in patients will greatly assist the phenotyping of patients for choosing treatments that produce analgesia by normalizing hyperexcitable central neural activity.
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Fibromyalgia and Overlapping Disorders: The Unifying Concept of Central Sensitivity Syndromes
TL;DR: CSS is an important new concept that embraces the biopsychosocial model of disease and seems to have important significance for new directions for research and patient care involving physician and patient education.
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Central Sensitivity Syndromes: A New Paradigm and Group Nosology for Fibromyalgia and Overlapping Conditions, and the Related Issue of Disease versus Illness
TL;DR: CSS seems to be a useful paradigm and an appropriate terminology for FMS and related conditions, and the disease-illness, as well as organic/non-organic dichotomy, should be rejected.
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Myofascial trigger points show spontaneous needle EMG activity.
TL;DR: The authors hypothesize that TrPs are caused by sympathetically activated intrafusal contractions.