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The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging
Andre E. Merbach,Éva Tóth +1 more
TLDR
This paper presents physical principles of Medical Imaging by Nuclear Magnetic Resonance and EPR Methods in Contrast Agent Research: Examples from GdA+ Chelates, a comparison of Frequency and Frequency Aspects of Lanthanide(III) Complexes.Abstract:
Contributors. Preface. Physical Principles of Medical Imaging by Nuclear Magnetic Resonance (S. Mansson and A. Bjornerud). Relaxivity of Gadolinium (III) Complexes: Theory and Mechanism (E. Toth, et al.). Synthesis of MRI Contrast Agents I: Acyclic Ligands. (P. Anelli and L. Lattuada). Synthesis of MRI Contrast Agents II: Macrocyclic Ligands. (V. Jacques and J. Desreux). Protein--Bound Metal Chelates (S. Aime, et al.). Stability and Toxicity of Contrast Agents (E. Brucher and A. Sherry). Computational Studies Related to Gd(III)--Based Contrast Agents (D. Sulzle, et al.). Structure and Dynamics of Gadolinium--Based Contrast Agents (J. Peters, et al). Multi--Frequency and High--Frequency EPR Methods in Contrast Agent Research: Examples from GdA+ Chelates (R. Clarkson, et al). Particulate Magnetic Contrast Agents (R. Muller, et al). Photophysical Aspects of Lanthanide(III) Complexes (J. Bruce, et al).read more
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Lanthanide-containing molecular and supramolecular polymetallic functional assemblies.
TL;DR: Detailed studies of lanthanide solvates with water or acetonitrile suggest that trivalent lanthanides display a tendency to adopt nine-coordinate tricapped trigonal prismatic (TTP) arrangements around the metal ion in the solid state.