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The chemistry of indoles

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The article was published on 1970-01-01 and is currently open access. It has received 909 citations till now.

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Indole synthesis – something old, something new

TL;DR: In this article, a general approach would start from a mono-functionalized arene such as an aniline or halobenzene, followed by cyclization with C-C or C-N bond formation to an unactivated C-H bond.
Journal ArticleDOI

Bis- and Trisindolylmethanes (BIMs and TIMs)†

TL;DR: The main purpose of this review is to provide a comprehensive summary of the various synthetic strategies to synthesize BIMs and TIMs.
Journal ArticleDOI

Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view.

TL;DR: An overview of the chemistry, biology, and toxicology of indoles focusing on their application as drugs is provided to corroborate the information available on the natural indole alkaloids, indole based FDA approved drugs and clinical trial candidates having diverse therapeutic implementations.
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