Journal ArticleDOI
The Department of Health and Human Services.
TLDR
This letter is in response to your two Citizen Petitions, requesting that the Food and Drug Administration (FDA or the Agency) require a cancer warning on cosmetic talc products.Abstract:
This letter is in response to your two Citizen Petitions dated November 17, 1994 and May 13, 2008, requesting that the Food and Drug Administration (FDA or the Agency) require a cancer warning on cosmetic talc products. Your 1994 Petition requests that all cosmetic talc bear labels with a warning such as \"Talcum powder causes cancer in laboratory animals. Frequent talc application in the female genital area increases the risk of ovarian cancer.\" Additionally, your 2008 Petition requests that cosmetic talcum powder products bear labels with a prominent warning such as: \"Frequent talc application in the female genital area is responsible for major risks of ovarian cancer.\" Further, both of your Petitions specifically request, pursuant to 21 CFR 1 0.30(h)(2), a hearing for you to present scientific evidence in support of this petition.read more
Citations
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Alcoholic cardiomyopathy: incidence, clinical characteristics, and pathophysiology.
TL;DR: Alcohol abstinence, as well as the use of specific heart failure pharmacotherapies, is critical in improving ventricular function and outcomes in these patients.
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Child Maltreatment during the COVID-19 Pandemic: Consequences of Parental Job Loss on Psychological and Physical Abuse Towards Children
TL;DR: Job loss during the COVID-19 pandemic is a significant risk factor for child maltreatment and reframing coping may be an important buffer of this association on physical abuse and presents implications for maltreatment prevention.
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FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects.
TL;DR: The finding that fosB mutant mice completely lacked basal levels of the 35- to 37-kDa Fos-related proteins demonstrates that a Fos family member protein plays a functional role in behavioral responses to drugs of abuse and implicates fos B gene products as important determinants of cocaine abuse.
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Key Determinants of the Health and Well-Being of Men and Boys
TL;DR: It is suggested that men’s greatest health risks are the result of modifiable factors, and that efforts to address these factors through practice, policy, and research could contribute to enhanced health conditions for men and boys, as well as to healthier families and communities.
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Nighttime insomnia treatment and education for Alzheimer's disease: a randomized, controlled trial.
TL;DR: In this article, the authors evaluated whether a comprehensive sleep education program (Nighttime Insomnia Treatment and Education for Alzheimer's Disease (NITE-AD)) could improve sleep in dementia patients living at home with their family caregivers.
References
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An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial
TL;DR: This herbal mixture of Ma Huang and Guarana effectively promoted short-term weight and fat loss and safety with long-term use requires further investigation.
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Historical background of clinical trials involving women and minorities
TL;DR: A historical context for the difficult ethical and clinical issues associated with the inclusion of women and members of minority groups in clinical research is provided.
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Reported Complications of Silicone Gel Breast Implants: An Epidemiologic Review
Barbara G. Silverman,S. L. Brown,Roselie A. Bright,Ronald G. Kaczmarek,J B Arrowsmith-Lowe,D A Kessler +5 more
TL;DR: This review presents an overview of the most common adverse outcomes that have been reported with silicone gel breast implants and focuses on silicone breast implants rather than saline-filled implants, which have been the focus of the greatest health concerns.
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Serum levels of TCDD and dioxin-like chemicals in Rhesus monkeys chronically exposed to dioxin: correlation of increased serum PCB levels with endometriosis
Sherry E. Rier,Wayman E. Turner,Dan C. Martin,Richard W Morris,George W. Lucier,George C. Clark +5 more
TL;DR: It is demonstrated that the serum levels of TCDD and specific dioxin-like PHAH congeners were increased in TCDd-treated animals with endometriosis 13 years after the T CDD exposure, and the severity of disease correlated with the serum concentration of 3,3',4,4'-TCB.
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Aiding troubled employees: The prevalence, cost, and characteristics of employee assistance programs in the United States
Tyler Hartwell,Paul D. Steele,Michael T. French,Frank J. Potter,Nathaniel F. Rodman,Gary A. Zarkin +5 more
TL;DR: EAPs are becoming a more prevalent point of access to health care for workers with personal problems such as substance abuse, family problems, or emotional distress by worksite size, industry, and census region.