Journal ArticleDOI
The Department of Health and Human Services.
TLDR
This letter is in response to your two Citizen Petitions, requesting that the Food and Drug Administration (FDA or the Agency) require a cancer warning on cosmetic talc products.Abstract:
This letter is in response to your two Citizen Petitions dated November 17, 1994 and May 13, 2008, requesting that the Food and Drug Administration (FDA or the Agency) require a cancer warning on cosmetic talc products. Your 1994 Petition requests that all cosmetic talc bear labels with a warning such as \"Talcum powder causes cancer in laboratory animals. Frequent talc application in the female genital area increases the risk of ovarian cancer.\" Additionally, your 2008 Petition requests that cosmetic talcum powder products bear labels with a prominent warning such as: \"Frequent talc application in the female genital area is responsible for major risks of ovarian cancer.\" Further, both of your Petitions specifically request, pursuant to 21 CFR 1 0.30(h)(2), a hearing for you to present scientific evidence in support of this petition.read more
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Wound management for the 21st century: combining effectiveness and efficiency.
TL;DR: A basic understanding of the terminology and principles of Health Economics in relation to wound management might therefore be of interest.
Journal ArticleDOI
Improving care for patients with acute heart failure: before, during and after hospitalization
Martin R. Cowie,Stefan D. Anker,John G.F. Cleland,John G.F. Cleland,G. Michael Felker,Gerasimos Filippatos,Tiny Jaarsma,Patrick Jourdain,Eve Knight,Barry M. Massie,Piotr Ponikowski,Jose Lopez-Sendon +11 more
TL;DR: Recommendations from structured discussions among an author group of AHF experts in 2013 are presented, which suggest that routine EMTs should be considered as a first line of treatment for acute heart failure.
Journal ArticleDOI
The Prospective Relation between Dimensions of Anxiety and the Initiation of Adolescent Alcohol Use
TL;DR: Results indicate that it is important to consider specific dimensions of anxiety symptomatology when attempting to identify those individuals at risk for early initiation of alcohol use.
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How does light-intensity physical activity associate with adult cardiometabolic health and mortality? Systematic review with meta-analysis of experimental and observational studies
Sebastien F. M. Chastin,Marieke De Craemer,Katrien De Cocker,Lauren Powell,Jelle Van Cauwenberg,Jelle Van Cauwenberg,Philippa M. Dall,Mark Hamer,Emmanuel Stamatakis +8 more
TL;DR: Light-intensity physical activity could play a role in improving adult cardiometabolic health and reducing mortality risk and the modest volume of the prospective epidemiological evidence base and the moderate consistency between observational and laboratory evidence inhibits definitive conclusions.
Journal ArticleDOI
Efficacy and Tolerability of 3 Nonnucleoside Reverse Transcriptase Inhibitor–Sparing Antiretroviral Regimens for Treatment-Naive Volunteers Infected With HIV-1: A Randomized, Controlled Equivalence Trial
Jeffrey L. Lennox,Raphael J. Landovitz,Heather J. Ribaudo,Ighovwerha Ofotokun,Lumine H. Na,Catherine Godfrey,Daniel R. Kuritzkes,Manish Sagar,Todd T. Brown,Susan E. Cohn,Grace A. McComsey,Francesca T. Aweeka,Carl J. Fichtenbaum,Rachel M. Presti,Susan L. Koletar,David W. Haas,Kristine B. Patterson,Constance A. Benson,Bryan Baugh,Randi Y. Leavitt,James F. Rooney,Daniel Seekins,Judith S. Currier +22 more
TL;DR: Over 2 years, all 3 regimens attained high and equivalent rates of virologic control and tolerability and raltegravir was superior to both protease inhibitors.
References
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An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial
TL;DR: This herbal mixture of Ma Huang and Guarana effectively promoted short-term weight and fat loss and safety with long-term use requires further investigation.
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Historical background of clinical trials involving women and minorities
TL;DR: A historical context for the difficult ethical and clinical issues associated with the inclusion of women and members of minority groups in clinical research is provided.
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Reported Complications of Silicone Gel Breast Implants: An Epidemiologic Review
Barbara G. Silverman,S. L. Brown,Roselie A. Bright,Ronald G. Kaczmarek,J B Arrowsmith-Lowe,D A Kessler +5 more
TL;DR: This review presents an overview of the most common adverse outcomes that have been reported with silicone gel breast implants and focuses on silicone breast implants rather than saline-filled implants, which have been the focus of the greatest health concerns.
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Serum levels of TCDD and dioxin-like chemicals in Rhesus monkeys chronically exposed to dioxin: correlation of increased serum PCB levels with endometriosis
Sherry E. Rier,Wayman E. Turner,Dan C. Martin,Richard W Morris,George W. Lucier,George C. Clark +5 more
TL;DR: It is demonstrated that the serum levels of TCDD and specific dioxin-like PHAH congeners were increased in TCDd-treated animals with endometriosis 13 years after the T CDD exposure, and the severity of disease correlated with the serum concentration of 3,3',4,4'-TCB.
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Aiding troubled employees: The prevalence, cost, and characteristics of employee assistance programs in the United States
Tyler Hartwell,Paul D. Steele,Michael T. French,Frank J. Potter,Nathaniel F. Rodman,Gary A. Zarkin +5 more
TL;DR: EAPs are becoming a more prevalent point of access to health care for workers with personal problems such as substance abuse, family problems, or emotional distress by worksite size, industry, and census region.