Journal ArticleDOI
The Department of Health and Human Services.
TLDR
This letter is in response to your two Citizen Petitions, requesting that the Food and Drug Administration (FDA or the Agency) require a cancer warning on cosmetic talc products.Abstract:
This letter is in response to your two Citizen Petitions dated November 17, 1994 and May 13, 2008, requesting that the Food and Drug Administration (FDA or the Agency) require a cancer warning on cosmetic talc products. Your 1994 Petition requests that all cosmetic talc bear labels with a warning such as \"Talcum powder causes cancer in laboratory animals. Frequent talc application in the female genital area increases the risk of ovarian cancer.\" Additionally, your 2008 Petition requests that cosmetic talcum powder products bear labels with a prominent warning such as: \"Frequent talc application in the female genital area is responsible for major risks of ovarian cancer.\" Further, both of your Petitions specifically request, pursuant to 21 CFR 1 0.30(h)(2), a hearing for you to present scientific evidence in support of this petition.read more
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Strategies for grouping per- and polyfluoroalkyl substances (PFAS) to protect human and environmental health
Ian T. Cousins,Jamie C. DeWitt,Juliane Glüge,Gretta Goldenman,Dorte Herzke,Rainer Lohmann,Mark A. Miller,Carla A. Ng,Martin Scheringer,Lena Vierke,Zhanyun Wang +10 more
TL;DR: This assessment provides the necessary context for grouping strategies such that they can be adopted as they are, or built on further, to protect human and environmental health from potential PFAS-related effects.
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Beyond the Stucco Tower: Design, Development, and Dissemination of the SPARK Physical Education Programs.
TL;DR: The SPARK (Sports, Play, and Active Recreation for Kids) programs for elementary and middle schools (1989-2000) and the ensuing efforts to disseminate those programs nationally (1994-present) are described in this paper.
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Subcutaneous administration of rituximab (MabThera) and trastuzumab (Herceptin) using hyaluronidase.
O Shpilberg,C Jackisch +1 more
TL;DR: Coformulation with rHuPH20 may enable effective, well-tolerated, cost-effective, and convenient SC administration of rituximab and trastuzumab.
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Health care workers' views about respirator use and features that should be included in the next generation of respirators.
TL;DR: Survey results indicated that health care workers seek respirators that are more comfortable, interfere less with breathing, diminish heat buildup, are disposable, and permit the user to have facial hair.
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Are Racial Disparities in Pancreatic Cancer Explained by Smoking and Overweight/Obesity?
Lauren D. Arnold,Alpa V. Patel,Yan Yan,Eric J. Jacobs,Michael J. Thun,Eugenia E. Calle,Graham A. Colditz +6 more
TL;DR: The inability to attribute excess disease in Blacks to currently known risk factors, even when combined with suspected risks, points to yet undetermined factors that play a role in the disease process.
References
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An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial
TL;DR: This herbal mixture of Ma Huang and Guarana effectively promoted short-term weight and fat loss and safety with long-term use requires further investigation.
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Historical background of clinical trials involving women and minorities
TL;DR: A historical context for the difficult ethical and clinical issues associated with the inclusion of women and members of minority groups in clinical research is provided.
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Reported Complications of Silicone Gel Breast Implants: An Epidemiologic Review
Barbara G. Silverman,S. L. Brown,Roselie A. Bright,Ronald G. Kaczmarek,J B Arrowsmith-Lowe,D A Kessler +5 more
TL;DR: This review presents an overview of the most common adverse outcomes that have been reported with silicone gel breast implants and focuses on silicone breast implants rather than saline-filled implants, which have been the focus of the greatest health concerns.
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Serum levels of TCDD and dioxin-like chemicals in Rhesus monkeys chronically exposed to dioxin: correlation of increased serum PCB levels with endometriosis
Sherry E. Rier,Wayman E. Turner,Dan C. Martin,Richard W Morris,George W. Lucier,George C. Clark +5 more
TL;DR: It is demonstrated that the serum levels of TCDD and specific dioxin-like PHAH congeners were increased in TCDd-treated animals with endometriosis 13 years after the T CDD exposure, and the severity of disease correlated with the serum concentration of 3,3',4,4'-TCB.
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Aiding troubled employees: The prevalence, cost, and characteristics of employee assistance programs in the United States
Tyler Hartwell,Paul D. Steele,Michael T. French,Frank J. Potter,Nathaniel F. Rodman,Gary A. Zarkin +5 more
TL;DR: EAPs are becoming a more prevalent point of access to health care for workers with personal problems such as substance abuse, family problems, or emotional distress by worksite size, industry, and census region.