Journal ArticleDOI
The Detection of Microemboli in the Middle Cerebral Artery during Cardiopulmonary Bypass: A Transcranial Doppler Ultrasound Investigation Using Membrane and Bubble Oxygenators
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TLDR
The ultrasound index for detecting gaseous microemboli (MEI) indicated the presence of suchmicroemboli in 22 of the 27 patients during insertion of the aortic cannula during cardiopulmonary bypass surgery, supporting the assumption that the MEI is providing quantitative information regarding the existence of gaseously emboli in the middle cerebral artery.About:
This article is published in The Annals of Thoracic Surgery.The article was published on 1987-09-01. It has received 269 citations till now. The article focuses on the topics: Bubble oxygenator & Membrane oxygenator.read more
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Microemboli in Cerebral Circulation and Alteration of Cognitive Abilities in Patients With Mechanical Prosthetic Heart Valves
TL;DR: Studying attention and memory, which are among the most impaired cognitive functions as demonstrated in previous studies, in patients with an MHV found Alteration of episodic memory can be attributed to a long-term effect of the surgical procedure and Deterioration of workingMemory can be related to the presence of cerebral microemboli in MHV patients.
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Recognition and Prevention of Neurological Complications in Pediatric Cardiac Surgery
TL;DR: Recent studies in animal models of child surgery and in children have produced some evidence to guide management to ensure the optimal cerebral as well as cardiac outcome, including methylprednisolone to protect the spinal cord.
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2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery.
Gudrun Kunst,Gudrun Kunst,Milan Milojevic,Milan Milojevic,Christa Boer,Filip De Somer,Tomas Gudbjartsson,Jenny van den Goor,Timothy J. Jones,Vladimir V. Lomivorotov,Frank Merkle,Marco Ranucci,Luc Puis,Alexander Wahba,Peter Alston,David Fitzgerald,Aleksandar Nikolic,Francesco Onorati,Bodil Steen Rasmussen,Staffan Svenmarker +19 more
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Quantification of ultrasound emboli signals in patients with cardiac and carotid disease.
TL;DR: There is promise of being able to distinguish emboli on the basis of power measurements, and emboli of different sources appear to have different ultrasonic characteristics, which are likely to be based on composition and size.
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Comparison of pH-stat and alpha-stat cardiopulmonary bypass on cerebral oxygenation and blood flow in relation to hypothermic circulatory arrest in piglets.
TL;DR: Cortical deoxygenation during hypothermic arrest was slower after pH-Stat CPB, and pH-stat bypass increased the prearrest ScO(2) and arrest ScO (2) half-life, to increase the cortical oxygen supply and slow cortical oxygen consumption.
References
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Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries
TL;DR: This transcranial Doppler method is of particular value for the detection of vasospasm following subarachnoid hemorrhage and for evaluating the cerebral circulation in occlusive disease of the carotid and vertebral arteries.
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Complement activation during cardiopulmonary bypass. Evidence for generation of C3a and C5a anaphylatoxins
Dennis E. Chenoweth,Steven W. Cooper,Tony E. Hugli,Robert W. Stewart,Eugene H. Blackstone,John W. Kirklin +5 more
TL;DR: It is concluded that the complement-derived inflammatory mediators C3a and C5a produced during extracorporeal circulation may contribute to the pathogenesis of "post-pump syndromes."
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Dependency of Blood Flow Velocity in the Middle Cerebral Artery on End-Tidal Carbon Dioxide Partial Pressure—A Transcranial Ultrasound Doppler Study:
TL;DR: The end-tidal carbon dioxide partial pressure response curves for the flow velocity in the middle cerebral artery were studied in 31 normal subjects with transcranial Doppler techniques and an exponential curve with an exponent of 0.034 mm Hg−1 was found to be a good fit to the recorded data.
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Transcranial measurement of blood velocities in the basal cerebral arteries using pulsed Doppler ultrasound: velocity as an index of flow.
TL;DR: Blood velocities have been measured transcranially, at small Doppler angles, in the middle cerebral artery of normal volunteers, and indicates that changes in middle cerebral blood velocity may be used to monitor changes in flow.
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Deleterious effects of cardiopulmonary bypass. A prospective study of bubble versus membrane oxygenation.
TL;DR: Several deleterious hematologic consequences of cardiopulmonary bypass can be minimized by the use of a membrane oxygenator, however, complement activation remains a potential risk factor even in membrane oxygenators patients and requires further investigation to obtain better hemocompatible materials for cardiopULmonary bypass circuits.