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Journal ArticleDOI

The effect of a lower target blood pressure on the progression of kidney disease: long-term follow-up of the modification of diet in renal disease study.

TLDR
The effects of a low target blood pressure on the onset of kidney failure and all-cause mortality was evaluated through extended follow-up after completion of the MDRD Study and it was recommended that participants with proteinuria greater than 1 g/d have a lower targetBlood pressure.
Abstract
The optimal blood pressure to slow progression of chronic kidney disease is not known. In this report of long-term follow-up of patients with a moderately to severely decreased glomerular filtratio...

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Citations
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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
References
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Journal ArticleDOI

The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The collaborative study group

TL;DR: Captopril protects against deterioration in renal function in insulin-dependent diabetic nephropathy and is significantly more effective than blood-pressure control alone.
Journal ArticleDOI

The Effects of Dietary Protein Restriction and Blood-Pressure Control on the Progression of Chronic Renal Disease

TL;DR: Restricting protein intake and controlling hypertension delay the progression of renal disease in animals and in patients with various chronic renal diseases.
Journal ArticleDOI

Blood pressure control, proteinuria, and the progression of renal disease. The Modification of Diet in Renal Disease Study.

TL;DR: The MDRD Study compared the rates of decline in glomerular filtration rate in 840 patients with a diverse array of renal diseases who were randomly assigned to either a usual or a low blood pressure goal and evaluated the effect of blood pressure on changes in proteinuria.
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