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Journal ArticleDOI

The effect of turmeric extracts on inflammatory mediator production.

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TLDR
Fractions and subfractions of turmeric extracts collected via preparative HPLC had differing biological activity, indicating interaction of the compounds within the fraction to produce an anti-inflammatory effect.
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This article is published in Phytomedicine.The article was published on 2005-06-15. It has received 222 citations till now. The article focuses on the topics: Bisdemethoxycurcumin & Curcuma.

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Book ChapterDOI

Curcumin: The Indian solid gold

TL;DR: Curcumin has been shown to exhibit antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, and anticancer activities and thus has a potential against various malignant diseases, diabetes, allergies, arthritis, Alzheimer's disease, and other chronic illnesses.
Journal ArticleDOI

Shear-thinning hydrogels for biomedical applications

TL;DR: This review aims to highlight the range of injectable shear-thinning hydrogel systems being developed, with a focus on the various mechanisms of formation and shear -thinning and their use in biomedical applications.
Journal ArticleDOI

"Spicing up" of the immune system by curcumin.

TL;DR: Curcumin’s reported beneficial effects in arthritis, allergy, asthma, atherosclerosis, heart disease, Alzheimer's disease, diabetes, and cancer might be due in part to its ability to modulate the immune system, and these findings warrant further consideration of curcumin as a therapy for immune disorders.
Journal ArticleDOI

Encapsulation of curcumin in self-assembling peptide hydrogels as injectable drug delivery vehicles

TL;DR: The rate of curcumin release and its consequent therapeutic efficacy can be conveniently modulated as a function of the concentration of the MAX8 peptide.
Journal ArticleDOI

Multitargeting by turmeric, the golden spice: From kitchen to clinic

TL;DR: In clinical trials, turmeric has shown efficacy against numerous human ailments including lupus nephritis, cancer, diabetes, irritable bowel syndrome, acne, and fibrosis, and a spice originally common in the kitchen is now exhibiting activities in the clinic.
References
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Journal Article

Anticancer potential of curcumin: preclinical and clinical studies.

TL;DR: Evidence has also been presented to suggest that curcumin can suppress tumor initiation, promotion and metastasis, and Pharmacologically,Curcumin has been found to be safe.
Book

Inflammation: Basic principles and clinical correlates

TL;DR: This poster describes the cellular components of Inflammation, the mechanisms of response to inflammation, and the role of cytokines in the regulation of these components.
Journal ArticleDOI

Pharmacology of Curcuma longa

TL;DR: It appears that when given orally, curcumin is far less active than after i.p. administration, and systemic effects seem to be questionable after oral application except that they occur at very low concentrations ofCurcumin, which does not exclude a local action in the gastrointestinal tract.
Journal ArticleDOI

Stability of curcumin in buffer solutions and characterization of its degradation products

TL;DR: It was shown that decomposition was pH-dependent and occurred faster at neutral-basic conditions and vanillin, ferulic acid, feruloyl methane were identified as minor degradation products and the amount of vanillin increased with incubation time.
Journal ArticleDOI

Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

TL;DR: It is demonstrated that curcumin (diferuloylmethane), a known anti-inflammatory and anticarcinogenic agent, is a potent inhibitor of NF-κB activation.
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