The incidence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: all patients, idiopathic patients, and patients with severe ADAMTS-13 deficiency.
Deirdra R. Terrell,Lance A. Williams,Sara K. Vesely,Bernhard Lämmle,Johanna A. Kremer Hovinga,James N. George +5 more
TLDR
In all three categories, the incidence rates were greater for women and for blacks, and the greater incidence among women and blacks is comparable with their increased risk for other autoimmune disorders.About:
This article is published in Journal of Thrombosis and Haemostasis.The article was published on 2005-07-01 and is currently open access. It has received 303 citations till now. The article focuses on the topics: Rate ratio & Incidence (epidemiology).read more
Citations
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Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies.
Marie Scully,Beverley J. Hunt,Sylvia Benjamin,Ri Liesner,Peter Rose,Flora Peyvandi,Betty Y.Y. Cheung,Samuel J. Machin +7 more
TL;DR: The objective of this guideline is to provide healthcare professionals with clear, up-to-date, and practical guidance on the management of TTP and relatedThrombotic microangiopathies, defined by thrombocytopenia, microangypathic haemolytic anaemia (MAHA) and small vessel thromBosis.
Journal ArticleDOI
Thrombotic Thrombocytopenic Purpura
TL;DR: A 40-year-old obese black woman has had weakness and epigastric pain for several weeks and diarrhea and vomiting for four days, and the physical examination is normal except for abdominal tenderness.
Journal ArticleDOI
Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura.
TL;DR: Intensive immunosuppressive therapy with rituximab appears to be effective as salvage therapy, and ongoing clinical trials should determine whether adjuvant ritUXimab with plasma exchange also is beneficial at first diagnosis.
Journal ArticleDOI
Survival and relapse in patients with thrombotic thrombocytopenic purpura.
TL;DR: The Oklahoma TTP Registry is a population-based inception cohort of all 376 consecutive patients with an initial episode of clinically diagnosed TTP, and ADAMTS13 deficiency during remission was not clearly related to subsequent relapse.
Journal ArticleDOI
How I treat patients with thrombotic thrombocytopenic purpura: 2010
TL;DR: A subgroup of patients who appear to benefit from treatment with corticosteroids and other immunosuppressive agents in addition to plasma exchange but who have a high risk for relapse are defined.
References
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Journal ArticleDOI
Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura.
Gail Rock,Kenneth H. Shumak,Noel A. Buskard,Victor S. Blanchette,John G. Kelton,Rama C. Nair,Robert A. Spasoff +6 more
TL;DR: A prospective randomized trial comparing plasma exchange with plasma infusion for the treatment of thrombotic throm bocytopenic purpura finds plasma exchange is more effective than plasma infusion.
Journal ArticleDOI
von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic Syndrome
Miha Furlan,Rodolfo Robles,Miriam Galbusera,Giuseppe Remuzzi,Paul A. Kyrle,Brigitte Brenner,Manuela Krause,Inge Scharrer,Volker Aumann,Uwe Mittler,Max Solenthaler,Bernhard Lämmle +11 more
TL;DR: In this article, the authors investigated the prevalence of von Willebrand factor-cleaving protease deficiency in patients with familial and non-familial forms of thrombocytopenic purpura and hemolytic-uremic syndrome.
Von willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome
M Iha F Urlan,R Odolfo R Obles,G Iuseppe R Emuzzi,P Aul A. K Yrle,B Rigitte,B Renner,M Anuela K Rause,I Nge S Charrer,V Olker A Umann,M Ax S Olenthaler,Ernhard L Ämmle +10 more
Journal ArticleDOI
Comparison of Plasma Exchange With Plasma Infusion in the Treatment of Thrombotic Thrombocytopenia Purpura
Gail Rock,Kenneth H. Shumak,Noel A. Buskard,Victor S. Blanchette,John G. Kelton,Rama C. Nair,Robert A. Spasoff +6 more
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