Journal ArticleDOI
The Influence of Age and Sex on Skin Thickness, Skin Collagen and Density
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TLDR
Skin collagen decreased with age and was less in the females at all ages and variations in collagen density in disease limit the use of dermal thickness as a guide to changes in its collagen content.Abstract:
Forearm skin collagen, dermal thickness and collagen density were measured in a large number of normal subjects as a standard reference for future studies. Skin collagen decreased with age and was less in the females at all ages. There is a direct relationship between skin collagen and dermal thickness but variations in collagen density in disease limit the use of dermal thickness as a guide to changes in its collagen content.read more
Citations
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Journal ArticleDOI
The environment and skin aging
TL;DR: The skin is the body's first line of defense against the environment: many of the effects of exposure on the integument begin at an early age, continuing throughout one’s lifetime, and they are superimposed on the inevitable and biological changes of intrinsic aging.
Journal ArticleDOI
A prospective, randomized, double-blind, placebo-controlled study on the influence of a hormone replacement therapy on skin aging in postmenopausal women
Paul-Gunther Sator,M. O. Sator,Schmidt Jb,H. Nahavandi,S. Radakovic,Johannes C. Huber,Hönigsmann H +6 more
TL;DR: Improvements showed improvements in the parameters involved in skin aging in the HRT group as compared to baseline, and a positive effect on aging skin can be observed.
Journal ArticleDOI
Characteristics of skin wrinkling and dermal changes induced by repeated application of squalene monohydroperoxide to hairless mouse skin.
TL;DR: Results clearly suggest that the wrinkling and changes in dermal collagen content induced by Sq-OOH are qualitatively different to those induced by UVB exposure, particularly with regard to collagen content.
Journal ArticleDOI
A review of the effects of ageing on skin integrity and wound healing
TL;DR: The anatomy of the skin and the effects of ageing on the tissues are discussed and some guidance on skin assessment and the basics of skin care is offered.
Journal ArticleDOI
Repair of photoaged dermal matrix by topical application of a cosmetic ‘antiageing’ product
Rachel E.B. Watson,S.P. Long,J.J. Bowden,J.Y. Bastrilles,S.P. Barton,Christopher E.M. Griffiths +5 more
TL;DR: This work has shown that topical treatment with all‐trans retinoic acid (RA) can repair photoaged dermal matrix; this is regarded as the ‘gold standard’ against which repair agents are judged.
References
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Journal ArticleDOI
The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.
TL;DR: Method has been applied to a study of hydroxyproline distribution in cell particulates, tissue fluids, and purified plant and animal proteins, and significant amounts of hydroXYproline were found in crystalline preparations of pepsin, elastase.
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A modified radiographic method for measuring skin thickness.
TL;DR: A modified radiographic method for measuring skin thickness has been described and has given consistent results, and it is suggested that this method will be of value in studying conditions in which changes in skin thickness are to be expected.
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Osteoporosis, skin collagen, and androgen.
TL;DR: Total skin collagen was found to be decreased in untreated patients with osteoporosis, particularly women, but increased after treatment with androgens in women, suggesting decreased body collagen may possibly be a primary defect in osteopsorosis.
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Roentgenographic visualization and measurement of skin thickness and its diagnostic application in acromegaly.
TL;DR: Some relatively simple methods for visualization and accurate measurement of skin thickness and to give some preliminary results on their application are described.