Journal ArticleDOI
The past, present and future of augmentation cystoplasty
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The largest ever study of its kind has been conducted on the role of language and culture in the development of Alzheimer's disease and its effects on physical and mental health.Abstract:
What's known on the subject? And what does the study add? There is a wealth of evidence on the development, indications, outcomes and complications of augmentation cystoplasty (AC). Over the last decade, new evidence has been emerging to influence our clinical practice and application of this technique. AC is indicated as part of the treatment pathway for both neurogenic and idiopathic detrusor overactivity, usually where other interventions have failed or are inappropriate. The most commonly used technique remains augmentation with a detubularised patch of ileum (ileocystoplasty). Controversy persists over the role of routine surveillance following ileocystoplasty for the detection of subsequent bladder carcinoma; however the indication for surveillance after gastrocystoplasty is clearer due to a rising incidence of malignancy in this group. Despite a reduction in the overall numbers of AC operations being performed, it clearly still has a role to play, which we re-examine with contemporary studies from the last decade.read more
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Journal ArticleDOI
Neurogenic bladder in spinal cord injury patients.
Waleed Al Taweel,Raouf M. Seyam +1 more
TL;DR: The current literature pertaining to the pathology and management of neurogenic bladder dysfunction in patients with spinal cord injury is summarized.
Journal ArticleDOI
Bladder tissue regeneration using acellular bi-layer silk scaffolds in a large animal model of augmentation cystoplasty.
Duong Tu,Yeun Goo Chung,Eun Seok Gil,Abhishek Seth,Abhishek Seth,Debra Franck,Vivian Cristofaro,Vivian Cristofaro,Vivian Cristofaro,Maryrose P. Sullivan,Maryrose P. Sullivan,Maryrose P. Sullivan,Dolores Di Vizio,Dolores Di Vizio,Dolores Di Vizio,Pablo Gomez,Pablo Gomez,Rosalyn M. Adam,Rosalyn M. Adam,David L. Kaplan,Carlos R. Estrada,Carlos R. Estrada,Joshua R. Mauney,Joshua R. Mauney +23 more
TL;DR: Ex vivo organ bath studies demonstrated that regenerated tissues supported by both silk matrices displayed contractile responses to carbachol, α,β-methylene-ATP, KCl, and electrical field stimulation similar to controls.
Journal ArticleDOI
The performance of silk scaffolds in a rat model of augmentation cystoplasty.
Abhishek Seth,Yeun Goo Chung,Eun Seok Gil,Duong Tu,Debra Franck,Dolores Di Vizio,Rosalyn M. Adam,Rosalyn M. Adam,David L. Kaplan,Carlos R. Estrada,Carlos R. Estrada,Joshua R. Mauney,Joshua R. Mauney +12 more
TL;DR: Cystometric analyses at 10 weeks post-op revealed that animals implanted with the FF matrix configuration displayed superior urodynamic characteristics including compliance, functional capacity, as well as spontaneous non voiding contractions consistent with control levels, demonstrating that variations in scaffold processing techniques can influence the in vivo functional performance of silk matrices in bladder reconstructive procedures.
Journal ArticleDOI
Cumulative incidence of outcomes and urologic procedures after augmentation cystoplasty
TL;DR: Outcomes of interest and urologic procedures after AC are common and can be used to counsel patients and families about expectations after AC, and collaboration efforts are needed to further reduce morbidity.
Journal ArticleDOI
Biomatrices for bladder reconstruction.
Hsueh Kung Lin,Sundararajan V. Madihally,Blake W. Palmer,Dominic Frimberger,Kar Ming Fung,Bradley P. Kropp +5 more
TL;DR: For functional bladder regeneration, procedures for biomaterial fabrication, incorporation of biologically active agents, introduction of nanotechnology, and application of stem-cell technology need to be standardized.
References
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Journal ArticleDOI
Tissue-engineered autologous bladders for patients needing cystoplasty
TL;DR: Engineered bladder tissues, created with autologous cells seeded on collagen-polyglycolic acid scaffolds, and wrapped in omentum after implantation, can be used in patients who need cystoplasty.
Journal ArticleDOI
Role of Bile Acid Malabsorption in Pathogenesis of Diarrhea and Steatorrhea in Patients with Ileal Resection: I. Response to cholestyramine or replacement of dietary long chain triglyceride by medium chain triglyceride
Alan F. Hofmann,J. Rainer Poley +1 more
TL;DR: Evidence is provided that a major cause of diarrhea in patients with ileal resection was the increased passage of bile acids into the colon, and a therapeutic program is described to treat this syndrome.
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Malignancies in Bladder Augmentations and Intestinal Conduits
R. Bruce Filmer,Julia R. Spencer +1 more
TL;DR: This work reviews the various reports on malignancies in bladder augmentations and urinary conduits and compares these data to those known about malignancy arising in the colon after ureterosigmoidostomy.
Journal ArticleDOI
Gastrocystoplasty: an alternative solution to the problem of urological reconstruction in the severely compromised patient.
TL;DR: Use of stomach has protected these patients from the development of new or worsened hyperchloremic acidosis and should be considered when lower urinary tract reconstruction is necessary in such compromised patients.
Journal ArticleDOI
Transitional cell carcinoma of the bladder following augmentation cystoplasty for the neuropathic bladder
Trevor M. Soergel,Mark P. Cain,Rosalia Misseri,Thomas A. Gardner,Michael O. Koch,Richard C. Rink +5 more
TL;DR: This study supports the hypothesis that bladder augmentation appears to be an independent risk factor for TCC, with a lag time of less than 20 years.