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Open AccessJournal ArticleDOI

The Physiological Principle of Minimum Work: I. The Vascular System and the Cost of Blood Volume.

Cecil D. Murray
- 01 Mar 1926 - 
- Vol. 12, Iss: 3, pp 207-214
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This article is published in Proceedings of the National Academy of Sciences of the United States of America.The article was published on 1926-03-01 and is currently open access. It has received 1820 citations till now. The article focuses on the topics: Blood volume.

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Journal ArticleDOI

Vascularization with trees matched canopy to canopy: Diagonal channels with multiple sizes

TL;DR: In this paper, the authors show how to configure the tree-tree architecture such that the single stream that flows through the vascularized body has access to every volume element, and the configuration is two trees matched canopy to canopy, and has freedom to morph in several directions.
Journal ArticleDOI

Numerical study of wall shear stress-based descriptors in the human left coronary artery

TL;DR: These descriptors aid the prediction of disturbed flow conditions in the vessels and play a significant role in the detection of potential zones of atherosclerosis development.
Journal ArticleDOI

Optimization of tree-shaped fluid networks with size limitations

TL;DR: The Lagrange multiplier method is applied to obtain a problem formulation in which the pipe diameters do not appear explicitly, and the global cost minimization approach is extended to the design of a porous architecture.
Journal ArticleDOI

Structure-function relation in the coronary artery tree: from fluid dynamics to arterial bifurcations.

TL;DR: This research presents a novel and scalable approaches that combine high-performance liquid chromatography and high-resolution 3D image analysis to characterize the dynamic response of the immune system to CSM.
Journal ArticleDOI

A computational model of oxygen transport in the cerebrocapillary levels for normal and pathologic brain function

TL;DR: The results demonstrated that a disproportionately large increase in blood supply is required for a small increase in the oxygen demand, which, in turn, is strongly dependent on the resting OEF, an important indicator for the brain oxygen metabolism under normal perfusion and misery-perfusion syndrome.
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