The Physiological Principle of Minimum Work: I. The Vascular System and the Cost of Blood Volume.
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This article is published in Proceedings of the National Academy of Sciences of the United States of America.The article was published on 1926-03-01 and is currently open access. It has received 1820 citations till now. The article focuses on the topics: Blood volume.read more
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Multi-generational analysis and visualization of the vascular tree in 3D micro-CT images
TL;DR: An environment for performing a complete study of coronary branching geometry and fluid transport in micro-CT rat heart images is proposed and quantitative measures for arterial-lumen cross-sectional area, inter-branch segment length, branch surface area and others are computed.
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Constructal theory: from thermodynamic and geometric optimization to predicting shape in nature
TL;DR: In this paper, a review of recent theoretical developments toward predicting macroscopic organization (the occurrence of shape and structure) in natural flow systems, animate and inanimate, is presented.
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Distribution of wall shear rate throughout the arterial tree: a case study.
TL;DR: A non-uniform distribution of wall shear rates throughout the arterial system is suggested, based on Murray's law, which is based on the principle of minimum work for steady flow.
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The eye, the kidney, and cardiovascular disease: old concepts, better tools, and new horizons.
TL;DR: Combining OCT’s deep imaging with the analytical power of deep learning represents the next frontier in defining what the eye can reveal about the kidney and broader cardiovascular health.
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An optimization principle for vascular radius including the effects of smooth muscle tone.
TL;DR: A theoretical analysis reveals that the proposed optimization principle predicts that the optimum shear stress on the vessel wall due to blood flow increases with blood pressure, which agrees qualitatively with published findings that the fluidShear stress in veins is significantly smaller than it is in arteries.