Journal ArticleDOI
The rubro-olivo-cerebello-rubral loop and postural tremor in the monkey☆
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TLDR
It is concluded that the interruption of the rubro-olivo-cerebello-rubral loop and its interconnections represents an important feature in the appearance of postural tremor.About:
This article is published in Journal of the Neurological Sciences.The article was published on 1970-07-01. It has received 78 citations till now. The article focuses on the topics: Postural tremor & Superior cerebellar peduncle.read more
Citations
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Animal Models of Action Tremor
TL;DR: Harmaline causes enhanced neuronal synchrony and rhythmicity in the inferior olive; this animal model, although as yet unproven, is the most popular one for essential tremor (ET).
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Primate models of dyskinesia: The experimental approach to the study of basal ganglia-related involuntary movement disorders
TL;DR: Dans cet article, l'accent a ete mis sur les etudes qui ont contribue a la comprehension des mecanismes neuronaux qui soutendent et induisent une dyskinesie.
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Monoamines in the human neostriatum: Topographic distribution in normals and in Parkinson's disease and their role in akinesia, rigidity, chorea, and tremor
S. Fahn,L.R. Libsch,R.W. Cutler +2 more
TL;DR: The uneven reduction of dopamine and serotonin appears to preclude the possibility of a defect in the transport of precursor amino-acids into brain and in the synthesis, storage, and degradation of the monoamines in Parkinson's disease.
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Isolated tremor and disruption of the nigrostriatal dopaminergic system: an 18F-dopa PET study.
TL;DR: The findings argue against an association between ET and PD, but support the existence of a "benign" tremulous variant of PD.
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Petit mal epilepsy and parkinsonian tremor: hypothesis of a common pacemaker.
TL;DR: The recognition of the overlapping neuronal mechanisms in petit mal epilepsy and parkinsonian tremor, and the multistage control of thalamic oscillation suggests that drugs effectively used inpetit mal attacks may be effective in levodopa-refractory parkinsonia, and conversely, epileptic patients may benefit from drugs acting on the extrapyramidal system.
References
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Journal Article
Evidence for the existence of monoamine-containing neurons in the central nervous system. i. demonstration of monoamines in the cell bodies of brain stem neurons.
Dahlstroem A,Fuxe K +1 more
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[Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system].
H. Ehringer,Oleh Hornykiewicz +1 more
TL;DR: The distribution of noradrenaline and dopamine in human adult and newborn brains has been investigated in this paper, where the greatest amounts of dopamine were found in the hypothalamus, the central gray matter of the mesencephalon, the reticular formation and in the area postrema.
Journal Article
Dopamine (3-hydroxytyramine) and brain function
TL;DR: A good case can be made for the concept that the physiological activity of the brain dopamine is quite different from that of brain norepinephrine, although there are as yet no experiments to positively show that dopamine is a true neuro-transmitter substance in the brain.
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Demonstration and mapping out of nigro-neostriatal dopamine neurons
TL;DR: The data give strong evidence for the existence of nigro-neostriatal dopamine neurons, which probably contain most or all of the dopamine present in the neostriatum.
Journal ArticleDOI
Influence of the substantia nigra on the catecholamine content of the striatum
L. J. Poirier,T. L. Sourkes +1 more
TL;DR: The evidence that a well-identified group of neurons exert through their efferent fibers a direct role in the elaboration of a specific substance (dopamine) in a distant structure (the striatum) contributes to a better understanding of brain circuitry.
Related Papers (5)
Striatal amines, experimental tremor and the effect of harmaline in the monkey.
Influence of the substantia nigra on the catecholamine content of the striatum
L. J. Poirier,T. L. Sourkes +1 more