Journal ArticleDOI
The structure and composition of the myxoviruses: II. Components released from the influenza virus particle by ether
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This article is published in Virology.The article was published on 1961-04-01. It has received 136 citations till now.read more
Citations
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Journal ArticleDOI
The occurrence of a subunit pattern in the unit membranes of club endings in mauthner cell synapses in goldfish brains
TL;DR: Observations additional to those previously reported on boutons terminaux and club endings on Mauthner cell lateral dendrites, primarily as seen in sections of permanganate-fixed material, are described.
Journal ArticleDOI
Morphology of the isolated hemagglutinin and neuraminidase subunits of influenza virus.
TL;DR: The BEL (A0) strain of influenza virus was disrupted with sodium dodecyl sulphate (SDS), and the hemagglutinin subunits were isolated by electrophoresis on cellulose acetate strips, suggesting that the “spikes” seen on the surface of influenzairus particles are of two morphologically distinct kinds.
Journal ArticleDOI
Structure of the Ribonucleoprotein of Influenza Virus
TL;DR: The ribonucleoprotein (RNP) internal components of influenza virus were separated into distinct size classes by sedimentation in glycerol gradients and examined by electron microscopy by using positive staining with uranyl acetate.
Book ChapterDOI
Genes and Proteins of the Influenza Viruses
TL;DR: The structure of the influenza virus hemagglutinin complexed with its receptor sialic acid has been elucidated, which may provide a basis for the rational design of antiviral drugs that would block viral attachment to cells.
Journal ArticleDOI
Symmetry in virus architecture.
R.W. Horne,P. Wildy +1 more
TL;DR: Geometrical aspects of particles have been discussed in the light of recent evidence and special attention has been given to the limitations of packing of morphological subunits (capsomeres) in the shells of virions with cubic symmetry.
References
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Journal ArticleDOI
A negative staining method for high resolution electron microscopy of viruses.
S. Brenner,R.W. Horne +1 more
TL;DR: A simple technique has been developed for the study of the external form and structure of virus particles by mixing virus preparations with 1% phosphotungstic acid adjusted to pH 7.5 and spraying directly onto electron microscope supporting films made from evaporated carbon.
Journal ArticleDOI
The structure and composition of the myxoviruses: I. Electron microscope studies of the structure of myxovirus particles by negative staining techniques
TL;DR: Intact and disrupted particles of Newcastle disease virus, mumps, and Sendai virus reveal the existence of three main components, and an inner structure has been observed arranged in the form of a helix resembling tobacco mosaic virus.
Journal ArticleDOI
Structure of the influenza virus; the relation between biological activity and chemical structure of virus fractions.
TL;DR: Influenza virus elementary bodies can be disintegrated by treatment with ether with the liberation of two types of smaller particle, soluble antigen and red cell agglutinin, which has properties suggesting that it is derived from the host cell.
Journal ArticleDOI
Structure and development of viruses observed in the electron microscope. III. Influenza virus.
TL;DR: It is suggested that the spherical form of the virus is the elemental infectious unit and that the filamentous form is largely or completely non-infective.
Related Papers (5)
The structure and composition of the myxoviruses: I. Electron microscope studies of the structure of myxovirus particles by negative staining techniques
A negative staining method for high resolution electron microscopy of viruses.
S. Brenner,R.W. Horne +1 more