The survival benefit of liver transplantation.
Robert M. Merion,Douglas E. Schaubel,Dawn M. Dykstra,Richard B. Freeman,Friedrich K. Port,Robert A. Wolfe +5 more
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TLDR
With 1 year post-transplant follow‐up, patients at lower risk of pre‐transplant death do not have a demonstrable survival benefit from liver transplant, and Liver transplant survival benefit at 1 year is concentrated among patients at higher risk ofPre‐trans transplant death.About:
This article is published in American Journal of Transplantation.The article was published on 2005-02-01 and is currently open access. It has received 770 citations till now. The article focuses on the topics: Liver transplantation & Lower risk.read more
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Characteristics associated with liver graft failure: the concept of a donor risk index.
Sandy Feng,Nathan P. Goodrich,Jennifer L. Bragg-Gresham,Dawn M. Dykstra,J. D. Punch,M. A. DebRoy,S. M. Greenstein,Robert M. Merion +7 more
TL;DR: A quantitative donor risk index was developed using national data from 1998 to 2002 to assess the risk of donor liver graft failure using seven donor characteristics that independently predicted significantly increased risk of graft failure.
Journal ArticleDOI
The model for end-stage liver disease (MELD)
Patrick S. Kamath,W. Ray Kim +1 more
TL;DR: The Model for End‐stage Liver Disease was initially created to predict survival in patients with complications of portal hypertension undergoing elective placement of transjugular intrahepatic portosystemic shunts and was validated subsequently as an accurate predictor of survival among different populations of patients with advanced liver disease.
Journal ArticleDOI
Evaluation for liver transplantation in adults: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation
TL;DR: The purpose of the current Guidelines is to provide an evidence-based set of recommendations for the evaluation of adult patients who are potentially candidates for LT, and they are intended to be flexible, in contrast to standards of care, which are inflexible policies to be followed in every case.
Journal ArticleDOI
EASL Clinical Practice Guidelines: Liver transplantation
Patrizia Burra,Andrew K. Burroughs,Ivo Graziadei,Jacques Pirenne,Juan Carlos Garcia Valdecasas,Paolo Muiesan,Didier Samuel,Xavier Forns +7 more
TL;DR: This Clinical Practice Guideline has been developed to assist physicians and other healthcare providers during the evaluation process of candidates for LT and to help them in the correct management of patients after LT.
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Organ Donation and Utilization in the United States, 1996–2005
Randall S. Sung,J. Galloway,Janet E. Tuttle-Newhall,T. Mone,R. Laeng,Chris E. Freise,Panduranga S. Rao +6 more
TL;DR: Issues directly related to the organ donation process, including donor consent, donor medical suitability, non‐recovery of organs, organs recovered but not transplanted, expanded criteria donors (ECD), and donation after cardiac death (DCD), are discussed.
References
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Comparison of Mortality in All Patients on Dialysis, Patients on Dialysis Awaiting Transplantation, and Recipients of a First Cadaveric Transplant
Robert A. Wolfe,Valarie B. Ashby,Edgar L. Milford,Akinlolu O. Ojo,Robert E. Ettenger,Lawrence Y. Agodoa,Philip J. Held,Friedrich K. Port +7 more
TL;DR: In this paper, the authors conducted a longitudinal study of mortality in 228,552 patients who were receiving long-term dialysis for end-stage renal disease, and 46,164 were placed on a waiting list for transplantation, 23,275 of whom received a first cadaveric transplant between 1991 and 1997.
Journal ArticleDOI
A model to predict survival in patients with end‐stage liver disease
Patrick S. Kamath,Russell H. Wiesner,Michael Malinchoc,Walter K. Kremers,Terry M. Therneau,Catherine L. Kosberg,Gennaro D'Amico,E. Rolland Dickson,M.B.A. W. Ray Kim M.D. +8 more
TL;DR: The MELD scale is a reliable measure of mortality risk in patients with end‐stage liver disease and suitable for use as a disease severity index to determine organ allocation priorities in patient groups with a broader range of disease severity and etiology.
Journal ArticleDOI
A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts.
Michael Malinchoc,Patrick S. Kamath,Fredric D. Gordon,Craig J. Peine,Jeffrey M. Rank,Pieter C.J. ter Borg +5 more
TL;DR: This Mayo TIPS model may predict early death following elective TIPS for either prevention of variceal rebleeding or for treatment of refractory ascites, superior to both the Child‐Pugh classification and the Child-Pugh score in predicting survival.
Journal ArticleDOI
Model for end-stage liver disease (MELD) and allocation of donor livers
Russell H. Wiesner,Erick B. Edwards,Richard B. Freeman,Ann M. Harper,Ray Kim,Patrick S. Kamath,Walter K. Kremers,John R. Lake,Todd K. Howard,Robert M. Merion,Robert A. Wolfe,Ruud A.F. Krom,Paul M. Colombani,Paige C. Cottingham,Stephen P. Dunn,John J. Fung,Douglas W. Hanto,Sue V. McDiarmid,John M. Rabkin,Lewis W. Teperman,Jeremiah G. Turcotte,Lynn Rothberg Wegman +21 more
TL;DR: Data suggest that the MELD score is able to accurately predict 3-month mortality among patients with chronic liver disease on the liver waiting list and can be applied for allocation of donor livers.
Journal ArticleDOI
A model to predict survival in patients with end-stage liver disease
Patrick S. Kamath,Russell H. Wiesner,Michael Malinchoc,Walter K. Kremers,Terry M. Therneau,Gennaro D'Amico,Catherine L. Kosberg,E. R. Dickson,W. R. Kim +8 more
TL;DR: The MELD scale is a reliable measure of mortality risk in patients with end-stage liver disease and suitable for use as a disease severity index to determine organ allocation priorities in patient groups with a broader range of disease severity and etiology.
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Model for end-stage liver disease (MELD) and allocation of donor livers
Russell H. Wiesner,Erick B. Edwards,Richard B. Freeman,Ann M. Harper,Ray Kim,Patrick S. Kamath,Walter K. Kremers,John R. Lake,Todd K. Howard,Robert M. Merion,Robert A. Wolfe,Ruud A.F. Krom,Paul M. Colombani,Paige C. Cottingham,Stephen P. Dunn,John J. Fung,Douglas W. Hanto,Sue V. McDiarmid,John M. Rabkin,Lewis W. Teperman,Jeremiah G. Turcotte,Lynn Rothberg Wegman +21 more