Journal ArticleDOI
The Synthesis of Oxytocin1
Vincent du Vigneaud,Charlotte Ressler,John M. Swan,Carleton W. Roberts,Panayotis G. Katsoyannis +4 more
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This article is published in Journal of the American Chemical Society.The article was published on 1954-06-01. It has received 380 citations till now.read more
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Journal ArticleDOI
Sequence-controlled polymers.
TL;DR: This work reviews the progress that has been made in making sequence-controlled polymers of increasing length and complexity and proposes some strategies for controlling sequences in chain-growth and step-growth polymerizations.
Journal ArticleDOI
Oxytocin: the Great Facilitator of Life
TL;DR: Many, if not most, of Oxt's functions, from social interactions (affiliation, aggression) and sexual behavior to eventual parturition, lactation and maternal behavior, may be viewed as specifically facilitating species propagation.
Book ChapterDOI
Experimental and theoretical aspects of protein folding.
Anfinsen Cb,Harold A. Scheraga +1 more
TL;DR: The development of conformational energy calculation procedures will enable the three-dimensional structure of a native protein to be predicted from the knowledge of its amino acid sequence and its interactions with the solvent in which it is dissolved.
Journal ArticleDOI
The Current State of Peptide Drug Discovery: Back to the Future?
TL;DR: An emphasis is placed on describing research efforts to overcome the inherent weaknesses of peptide drugs, in particular their poor pharmacokinetic properties, and how these efforts have been critical to the discovery, design, and subsequent development of novel therapeutics.
Journal ArticleDOI
The Oxytocin Receptor: From Intracellular Signaling to Behavior
Benjamin Jurek,Inga D. Neumann +1 more
TL;DR: The mechanisms of OXT expression and release, expression and binding of the OXTR in brain and periphery, OX TR-coupled signaling cascades, and their involvement in behavioral outcomes are discussed to assemble a comprehensive picture of the central and peripheral OXT system.