Journal ArticleDOI
Three-dimensional filling flow into a model left ventricle
TLDR
In this article, a numerical study of the three-dimensional fluid dynamics inside a model left ventricle during diastole is presented, which is modelled as a portion of a prolate spheroid with a moving wall, whose dynamics is externally forced to agree with a simplified waveform of the entering flow.Abstract:
A numerical study of the three-dimensional fluid dynamics inside a model left ventricle during diastole is presented. The ventricle is modelled as a portion of a prolate spheroid with a moving wall, whose dynamics is externally forced to agree with a simplified waveform of the entering flow. The flow equations are written in the meridian body-fitted system of coordinates, and expanded in the azimuthal direction using the Fourier representation. The harmonics of the dependent variables are normalized in such a way that they automatically satisfy the high-order regularity conditions of the solution at the singular axis of the system of coordinates. The resulting equations are solved numerically using a mixed spectral–finite differences technique. The flow dynamics is analysed by varying the governing parameters, in order to understand the main fluid phenomena in an expanding ventricle, and to obtain some insight into the physiological pattern commonly detected. The flow is characterized by a well-defined structure of vorticity that is found to be the same for all values of the parameters, until, at low values of the Strouhal number, the flow develops weak turbulence.read more
Citations
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Journal ArticleDOI
Characterization and Quantification of Vortex Flow in the Human Left Ventricle by Contrast Echocardiography Using Vector Particle Image Velocimetry
Geu Ru Hong,Gianni Pedrizzetti,Giovanni Tonti,Peng Li,Zhao Wei,Jin Kyung Kim,Abinav Baweja,Shizhen Liu,Namsik Chung,Helene Houle,Jagat Narula,Mani A. Vannan +11 more
TL;DR: It was feasible to quantify LV vorticity arrangement by CE using particle image velocimetry in normal subjects and those with LV systolic dysfunction, and the vortivity imaging by CE may serve as a novel approach to depict vortex, the principal quantity to assess the flow structure.
Journal ArticleDOI
Optimal Vortex Formation as a Unifying Principle in Biological Propulsion
TL;DR: In this article, the authors review the concept of optimal vortex formation and examine its relevance to propulsion in biological and bio-inspired systems, ranging from the human heart to underwater vehicles.
Journal ArticleDOI
The vortex--an early predictor of cardiovascular outcome?
TL;DR: It is postulate that maladaptive intracardiac vortex dynamics might modulate the progressive remodelling of the left ventricle towards heart failure and presents a new paradigm in cardiac function analysis, with the potential for sensitive risk identification of cardiac abnormalities.
Journal ArticleDOI
Echocardiographic particle image velocimetry: a novel technique for quantification of left ventricular blood vorticity pattern.
Arash Kheradvar,Helene Houle,Gianni Pedrizzetti,Giovanni Tonti,Todd Belcik,Muhammad Ashraf,Jonathan R. Lindner,Morteza Gharib,David J. Sahn +8 more
TL;DR: The E-PIV technique appears to be capable of evaluating the major flow features in the ventricles, however, the bounded spatial resolution of ultrasound imaging limits the small-scale features of ventricular flow to be revealed.
Journal ArticleDOI
Multiphysics and multiscale modelling, data-model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics.
Radomir Chabiniok,Radomir Chabiniok,Vicky Y. Wang,Myrianthi Hadjicharalambous,Liya Asner,Jack Lee,Maxime Sermesant,Ellen Kuhl,Alistair A. Young,Philippe Moireau,Martyn P. Nash,Dominique Chapelle,David Nordsletten +12 more
TL;DR: Developments in computational cardiac modelling are reviewed and how their integration with medical imaging data is providing new pathways for translational cardiac modelling.
References
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