Journal ArticleDOI
Total synthesis of deoxymannojirimycin and d-mannolactam via carbonylation of 5-vinyloxazolidin-2-ones
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TLDR
In this paper, the stereoselective synthesis of piperidine alkaloids deoxymannojirimycin and d -mannolactam from d -serine has been achieved.About:
This article is published in Tetrahedron.The article was published on 2003-01-13. It has received 34 citations till now. The article focuses on the topics: Carbonylation & Total synthesis.read more
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Recent advances in the synthesis of piperidones and piperidines
Journal ArticleDOI
Recent Advances in the Total Synthesis of Piperidine Azasugars
TL;DR: In this paper, a microreview of recent syntheses of polyhydroxylated piperidines is presented, focusing on recent synthesises of azasugars and their analogs.
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Recent advances in the chemistry of azapyranose sugars
Kamyar Afarinkia,Akmal Bahar +1 more
TL;DR: In this article, the natural occurrence and recent reported syntheses of azapyranose sugars are discussed, and a detailed report on the synthesis process is presented, covering the natural occurrences and synthesisation process.
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Utilizing Palladium-Stabilized Zwitterions for the Construction of N-Heterocycles.
TL;DR: Pd catalysis provides a convenient method for the generation of zwitterionic intermediates that offer significant opportunities for the synthesis of functionalized heterocycles with control of chemo-, regio- and stereo-selectivity.
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Access to Oxoquinoline Heterocycles by N‐Heterocyclic Carbene Catalyzed Ester Activation for Selective Reaction with an Enone
TL;DR: Organocatalytic ester activation is developed for a highly selective cascade reaction between saturated esters and amino enones that allows a single-step access to multicyclic oxoquinoline-type heterocycles with high enantiomeric ratios.
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Inhibitors of the Biosynthesis and Processing of N-Linked Oligosaccharide Chains
TL;DR: A number of inhibitors have been identified that interfere with glycoprotein biosynthesis, processing, or transport, such as tunicamycin, tridecaptin, and flavomycin this paper.
Inhibitors of the biosynthesis and processing of n-linked
TL;DR: A number of glycoproteins have oligosaccharides linked to protein in a GlcNAc----asparagine bond that are either of the complex, the high-mannose or the hybrid structure and a number of inhibitors have been identified that interfere with glycoprotein biosynthesis, processing, or transport.
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Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides
TL;DR: In vivo dMM inhibits the equivalent of the mannosidase IA/B activities and blocks conversion of high-mannose to complex oligosaccharides, which could prove to be a powerful way to manipulate carbohydrate structure in vivo.
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Glycosidase inhibition by plant alkaloids which are structural analogues of monosaccharides
Stephen V. Evans,Linda E. Fellows,T. K. M. Shing,T. K. M. Shing,George W. J. Fleet,George W. J. Fleet +5 more
TL;DR: In this article, the inhibitory properties of three plant alkaloids, deoxynojirimycin, 2,5-dihydroxymethyl-3,4-dhydroxypyrrolidine and 1,5 dideoxy-1,5 -imino-D -mannitol towards glycosidases from several sources have been compared.