Translational research: Crossing the valley of death
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A chasm has opened up between biomedical researchers and the patients who need their discoveries and whether the US National Institutes of Health can bridge the gap.Abstract:
A chasm has opened up between biomedical researchers and the patients who need their discoveries. Declan Butler asks how the ground shifted and whether the US National Institutes of Health can bridge the gap.read more
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Delivering affordable cancer care in high-income countries
Richard Sullivan,Jeffrey Peppercorn,Karol Sikora,John Zalcberg,Neal J. Meropol,Eitan Amir,David Khayat,Peter Boyle,Philippe Autier,Ian F. Tannock,Tito Fojo,Jim Siderov,Steve Williamson,Silvia Camporesi,J. Gordon McVie,Arnie Purushotham,Peter Naredi,Alexander M.M. Eggermont,Murray F. Brennan,Michael L. Steinberg,Mark De Ridder,Susan A. McCloskey,Dirk Verellen,Terence Roberts,Guy Storme,Rodney J. Hicks,Peter J. Ell,Bradford R. Hirsch,David P. Carbone,Kevin A. Schulman,Paul Catchpole,David Taylor,Jan Geissler,Nancy G Brinker,David O. Meltzer,David J. Kerr,Matti Aapro +36 more
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Journal ArticleDOI
Defining translational research: implications for training.
Doris M. Rubio,Ellie E. Schoenbaum,Linda S. Lee,David E. Schteingart,Paul R. Marantz,Karl E. Anderson,Lauren Dewey Platt,Adriana Baez,Karin Esposito +8 more
TL;DR: The authors argue that the approach to designing and evaluating the success of translational training programs must be flexible enough to accommodate the needs of individual institutions and individual trainees within the institutions but that it must also be rigorous enough to document that the program is meeting its short-, intermediate-, and long-term objectives and that its trainees are meeting preestablished competency requirements.
Journal ArticleDOI
When complexity science meets implementation science: a theoretical and empirical analysis of systems change
TL;DR: What implementation science can learn from complexity science is discussed, and some of the properties of healthcare systems that enable or constrain the goals the authors have for better, more effective, more evidence-based care are teased out.
Journal ArticleDOI
Financing Renewable Energy: Who is Financing What and Why it Matters
TL;DR: In this paper, the authors analyze the asset portfolios of different renewable energy technologies financed by different financial actors according to their size, skew and level of risk, and construct a heuristic index of risk that varies with the technology, time, and country of investment.
Journal ArticleDOI
Funding of US biomedical research, 2003-2008
E. Ray Dorsey,Jason de Roulet,Joel P. Thompson,Jason I. Reminick,Ashley Thai,Zachary White-Stellato,Christopher A. Beck,Benjamin P. George,Hamilton Moses +8 more
TL;DR: After a decade of doubling, the rate of increase in biomedical research funding slowed from 2003 to 2007, and after adjustment for inflation, the absolute level of funding from the National Institutes of Health and industry appears to have decreased by 2% in 2008.
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