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Open AccessJournal ArticleDOI

Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012

TLDR
There have been considerable changes in care for mothers in preterm labor and for extremely preterm infants since the 1990s, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network has monitored changes.
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European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2016 Update.

TL;DR: The third update of the European Guidelines for the Management of RDS by a European panel of expert neonatologists including input from an expert perinatal obstetrician based on available literature up to the beginning of 2016 is reported.
Journal ArticleDOI

Necrotizing enterocolitis: new insights into pathogenesis and mechanisms.

TL;DR: The current approach to the diagnosis and treatment of NEC is examined, an overview of the current knowledge regarding its molecular underpinnings is provided and advances made within the past decade towards the development of specific preventive and treatment strategies for this devastating disease are highlighted.
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Journal ArticleDOI

A Modified Poisson Regression Approach to Prospective Studies with Binary Data

TL;DR: Results from a limited simulation study indicate that this approach is very reliable even with total sample sizes as small as 100, and the method is illustrated with two data sets.
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Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with birth weights less than 1,500 gm

TL;DR: There were no significant differences between the infants with and without IVH in birth weight, gestational age, one- and five-minute Apgar scores, or the need for resuscitation at birth or for subsequent respiratory assistance.
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Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging

TL;DR: These studies support the use of combination antimicrobial therapy in the treatment of infants with NEC and suggest vigorous diagnostic and supportive measures are appropriate for Stage I infants.
Journal ArticleDOI

An overview of mortality and sequelae of preterm birth from infancy to adulthood.

TL;DR: Because mortality rates have fallen, the focus for perinatal interventions is to develop strategies to reduce long-term morbidity, especially the prevention of brain injury and abnormal brain development.
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