Journal ArticleDOI
Two compounds implicated in the function of the RC gene of Escherichia coli.
TLDR
Autoradiography has revealed in a stringent strain of E. coli two compounds that seem to be involved in the inhibition of the synthesis of RNA.Abstract:
Autoradiography has revealed in a stringent strain of E. coli two compounds that seem to be involved in the inhibition of the synthesis of RNA.read more
Citations
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Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
TL;DR: A historic perspective on the development of the field is provided, common trends are emphasized, and new directions in c-di-GMP research are highlighted that will give a deeper understanding of this truly universal bacterial second messenger.
Journal ArticleDOI
Recent functional insights into the role of (p)ppGpp in bacterial physiology
TL;DR: This Review summarizes recent insights on the molecular mechanisms governing the activity of the RelA/SpoT homologue (RSH) proteins, which are key players that regulate the cellular levels of (p)ppGpp.
Journal ArticleDOI
Cellular nucleotide measurements and applications in microbial ecology.
Journal ArticleDOI
Complete analysis of cellular nucleotides by two-dimensional thin layer chromatography.
Barry R. Bochner,Bruce N. Ames +1 more
TL;DR: These methods are used to analyze and inventory the nucleotide content of Salmonella typhimurium in balanced log phase growth and developed a set of enzymatic and chemical methods to be used in conjunction with the chromatographic separations for verifying the identity of nucleotide and characterizing novel nucleotides.
References
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Journal ArticleDOI
A genetic locus for the regulation of ribonucleic acid synthesis
Gunther S. Stent,Sydney Brenner +1 more
Journal ArticleDOI
The effect of guanosine diphosphate and triphosphate on the incorporation of labeled amino acids into proteins.
TL;DR: It has been found that guanosine dior triphosphate is required in addition to ATP for amino acid incorporation in an enzyme system from rat liver which catalyzes the incorporation of labeled amino acids into proteins under anaerobic conditions.
Journal ArticleDOI
The assimilation of amino-acids by bacteria. XV. Actions of antibiotics on nucleic acid and protein synthesis in Staphylococcus aureus.
E. F. Gale,Joan P. Folkes +1 more
TL;DR: Experimental conditions have been described which will enable the following processes to be studied in washed suspensions of Staphylococcus aureus: internal accumulation of free glutamic acid, extracellular accumulation of peptides containing glutamic Acid, accumulation of combined glutamicacid within the cells, and synthesis of protein and nucleic acid.
Journal ArticleDOI
Regulation of ribosomal and transfer RNA synthesis.
C.G. Kurland,O. Maaløe +1 more
TL;DR: The results suggest that the rate of RNA synthesis is determined by the internal amino acid concentration, and a protein present in log phase cells is necessary for and consumed during the synthesis of ribosomal RNA.
Journal ArticleDOI
The dependence of nucleic acid syntheses on the presence of amino acids in escherichia coli
TL;DR: A further study of the effects of amino acid deficiencies and chloromycetin inhibition, separately and together, might clarify the possible dependence of nucleic acid syntheses on protein synthesis.
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The Control of Ribonucleic Acid Synthesis in Escherichia coli: IV. RELEVANCE OF UNUSUAL PHOSPHORYLATED COMPOUNDS FROM AMINO ACID-STARVED STRINGENT STRAINS
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Michael Cashel,Barbara Kalbacher +1 more