Journal ArticleDOI
Tyrosine hydroxylase polymorphisms and bipolar affective disorder.
TLDR
A reported genetic association between bipolar affective disorder and DNA polymorphisms at the tyrosine hydroxylase gene is not confirmed and the combined allele frequencies in patients and controls are significantly different from the frequencies in the controls.About:
This article is published in Journal of Psychiatric Research.The article was published on 1991-01-01. It has received 44 citations till now. The article focuses on the topics: Tyrosine hydroxylase & Allele frequency.read more
Citations
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Journal ArticleDOI
Association Between the Tryptophan Hydroxylase Gene and Manic-depressive Illness
Frank Bellivier,Marion Leboyer,Philippe Courtet,Catherine Buresi,Béatrice Beaufils,D. Samolyk,Jean-François Allilaire,Josué Feingold,Jacques Mallet,Alain Malafosse +9 more
TL;DR: The involvement of the TPH gene in susceptibility to manic-depressive illness is suggested, although this preliminary result requires confirmation in further groups of patients and controls.
BookDOI
Genetic Research in Psychiatry
TL;DR: In this paper, a genetic research in psychiatry always becomes the most wanted book and many people are absolutely searching for this book and it means that many love to read this kind of book.
Journal ArticleDOI
Association study of bipolar disorder with candidate genes involved in catecholamine neurotransmission: DRD2, DRD3, DAT1, and TH genes.
Daniel Souery,Olivier Lipp,Brigite Mahieu,Karin Mendelbaum,Viviane De Martelaer,Christine Van Broeckhoven,Julien Mendlewicz +6 more
TL;DR: Despite strong evidence for genetic involvement in the etiology of affective disorders, linkage and association methodologies are still exploring the nature of genetic factors in these diseases, including candidate genes involved in catecholamine neurotransmission.
Journal ArticleDOI
Molecular linkage studies of bipolar disorders
TL;DR: There are several regions of the human genome that have been implicated repeatedly by independent investigators that are also implicated in genome scans of schizophrenia, suggesting that these two distinct nosological categories may share some genetic susceptibility.
Journal ArticleDOI
No evidence of association between dopamine D3 receptor gene and bipolar affective disorder.
M. Paola Piccardi,Giovanni Severino,Alberto Bocchetta,M. Antonietta Palmas,S. Ruiu,Maria Del Zompo +5 more
TL;DR: It is concluded that variations in this repeat at the DRD4 gene do not contribute to the genetic component of manic depression.
References
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Journal ArticleDOI
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
TL;DR: A technique for conveniently radiolabeling DNA restriction endonuclease fragments to high specific activity is described, and these "oligolabeled" DNA fragments serve as efficient probes in filter hybridization experiments.
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
TL;DR: In this article, a technique for conveniently radiolabeling DNA restriction endonuclease fragments to high specific activity is described, where DNA fragments are purified from agarose gels directly by ethanol precipitation and are then denatured and labeled with the large fragment of DNA polymerase I, using random oligonucleotides as primers.
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Genomic sequencing
George M. Church,Walter Gilbert +1 more
TL;DR: The genomic sequencing procedures are applicable to the analysis of genetic polymorphisms, DNA methylation at deoxycytidines, and nucleic acid-protein interactions at single nucleotide resolution.
Journal ArticleDOI
Research diagnostic criteria: Rationale and reliability.
TL;DR: The development and initial reliability studies of a set of specific diagnostic criteria for a selected group of functional psychiatric disorders, the Research Diagnostic Criteria (RDC), indicate high reliability for diagnostic judgments made using these criteria.
Journal ArticleDOI
On estimating the relation between blood group and disease.
TL;DR: The use of x is recommended instead of d as a criterion of differential incidence of disease in relation to blood group, and in all statistical computations it is best to transform x into its logarithm.