Showing papers in "Journal of Psychiatric Research in 1991"
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TL;DR: Examination of psychopathology in first degree relatives of children from a non-clinical longitudinal cohort identified at 21 months of age as inhibited or uninhibited and followed through the age of seven years provides additional support for the hypothesis linking behavioral inhibition with risk for anxiety disorder.
195 citations
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TL;DR: The Seasonal Pattern Assessment Questionnaire (SPAQ) successfully discriminated between groups expected to have high seasonality scores, such as winter-SAD, summer-S AD and subsyndromal winter- SAD, and normal controls.
150 citations
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TL;DR: The performance of two forms of version I of the Diagnostic Interview Schedule (DIS) computer screening interview were equivalent, and the decision to use either may be based on available resources and characteristics of the study population.
76 citations
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TL;DR: The data suggest that a blunted testosterone and an elevated cortisol secretion are state markers of acute depression, which normalize independently from sleep structure.
57 citations
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TL;DR: The results underscore a cautious approach to the interpretation of platelet serotonergic studies and suggest the usefulness of IMI or 5-HT as clinical markers should be re-evaluated.
45 citations
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TL;DR: A reported genetic association between bipolar affective disorder and DNA polymorphisms at the tyrosine hydroxylase gene is not confirmed and the combined allele frequencies in patients and controls are significantly different from the frequencies in the controls.
44 citations
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TL;DR: Results of this study suggest that area measures may not accurately represent three-dimensional structure size.
38 citations
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TL;DR: It was found that the SCL-90 was able both to identify and discriminate between the clinical groups and showed that although there is overlap between PTSD and obsessive-compulsive disorder, PTSD is, in fact, discriminated from all the other patient groups.
35 citations
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TL;DR: negative symptoms were specifically associated with reaction time slowing and variability in schizophrenics, but not in affective disorders, and an abbreviated version of the negative symptom scale was especially effective in separating groups.
34 citations
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TL;DR: Contigency table and correlation analyses reveal that subjective support and depressive symptoms are interrelated but separate constructs.
33 citations
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TL;DR: Relatives were reinterviewed six years after study entry and were no more likely than younger ones to lose diagnoses nor to postdate their ages of first MDD onset, evidence that memory artifacts are not solely responsible for the observed secular trends.
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TL;DR: It is established that unipolar depression constitutes one biological continuum characterized by a progression of lower CRH-induced ACTH responses, lower L-TRP levels, and higher postdexamethasone cortisol and ACTH values along the diagnostic spectrum.
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TL;DR: In migraine, there was no significant relationship between Bmax and depression or anxiety score on the self-rating Hospital Anxiety and Depression (HAD) Scale, suggesting that the reduction in Bmax is a concomitant of migraine itself rather than a manifestation of associated depression.
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TL;DR: Risks for psychiatric disorders (RDC) among first degree relatives of DSM-III schizophreniform, bipolar, and schizophrenic probands obtained from an epidemiologic sample using family history methods were examined and it was found that the relatives of schizophreniform probands had significantly higher rates of affective illnesses.
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TL;DR: The study found that whereas tyramine sulphate conjugation was significantly impaired in unipolar patients, values in the bipolars were similar to those of controls, providing further evidence for the biological difference between unipolar and bipolar depression.
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TL;DR: Low FT4I levels prospectively predicted more hospital admissions in the 12 months from index admission, and this was not due to past admissions predicting future admissions, adding to the growing literature on important relationships between thyroid hormones and treatment outcome in patients with affective disorders.
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TL;DR: The width ratio was most effective in distinguishing HD from AD patients when age was used as a covariate and no SSC measure was significantly correlated with cognitive status in HD, suggesting that atrophies of the frontal-temporal and basal forebrain areas are associated with cognitive decline in Alzheimer's Disease but not in Huntington's Disease.
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TL;DR: One of the newer scales of suicide risk devised by Plutchik and colleagues was tested to see if it could discriminate between levels of suicide ideation and suicide attempts and showed that the full scale did not adequately discriminate among groups.
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TL;DR: Patients with no family history of depression had significantly higher mean personality trait scores on the dependent and compulsive personality scales, and the clinical and theoretical implications of these findings are discussed.
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TL;DR: A significant suppressive effect of dexamethasone on prolactin levels is found and there are no significant differences either in pre- or postdexamethAsone prol actin, or in actual dexamETHasone-induced decrements in prolactIn between normal controls, melancholics, simple major or minor depressed subjects.