Journal ArticleDOI
Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function.
Christopher K. Willie,Francisco L. Colino,Damian M. Bailey,Yu-Chieh Tzeng,Gordon Binsted,Lee W. Jones,Mark J. Haykowsky,Judith Bellapart,Shigehiko Ogoh,Kurt J. Smith,Jonathan D. Smirl,Trevor A. Day,Samuel J. E. Lucas,Lindsay K. Eller,Philip N. Ainslie +14 more
TLDR
TCD is an efficient tool to access blood velocities within the cerebral vessels, cerebral autoregulation, cerebrovascular reactivity to CO(2), and neurovascular coupling in both physiological states and in pathological conditions such as stroke and head trauma.About:
This article is published in Journal of Neuroscience Methods.The article was published on 2011-03-30. It has received 460 citations till now. The article focuses on the topics: Cerebrovascular Physiology & Cerebral autoregulation.read more
Citations
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Journal ArticleDOI
Regional brain blood flow in man during acute changes in arterial blood gases
Christopher K. Willie,David B. MacLeod,Andrew D. Shaw,Andrew D. Shaw,Kurt J. Smith,Yu-Chieh Tzeng,Neil D. Eves,Keita Ikeda,J. Graham,Nia C. S. Lewis,Trevor A. Day,Philip N. Ainslie +11 more
TL;DR: During alterations in arterial carbon dioxide and oxygen, the large arteries changed diameter and blood flow to the brainstem changed more than that to the cortex.
Journal ArticleDOI
Transcranial Doppler ultrasound: technique and application.
TL;DR: TCD has established utility in the clinical diagnosis of a number of cerebrovascular disorders such as acute ischemic stroke, vasospasm, subarachnoid hemorrhage, sickle cell disease, as well as other conditions such as brain death.
Journal ArticleDOI
Neurovascular coupling in humans: Physiology, methodological advances and clinical implications
TL;DR: New guidelines for standardizing the assessment of neurovascular coupling in humans are presented and the utility of new automated software for neurov vascular coupling is demonstrated, which provides the capacity for coalescing repetitive trials and time intervals into single contours and extracting numerous metrics.
Journal ArticleDOI
Functional ultrasound imaging of the brain: theory and basic principles
TL;DR: A μDoppler ultrasound method able to detect and map the cerebral blood volume (CBV) over the entire brain with an important increase in sensitivity is presented and is the basis for a real-time functional ultrasound (fUS) imaging of the brain.
Journal ArticleDOI
Brain and visual perception: The story of a 25‐year collaboration
TL;DR: In this paper, the authors describe the background to their research in normal physicology and anatomy and anatomy, and three reviews of the work are given.PART I: INTRODUCTION and BIOGRAPHIES PART II: BACKGROUND TO RESEARCH PART III: NORMAL PHYSIOLOGY and ANATOMY PART IV: DEPRIVATION and DEVELOPMENT PART V: THREE this paper
References
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Journal ArticleDOI
Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries
TL;DR: This transcranial Doppler method is of particular value for the detection of vasospasm following subarachnoid hemorrhage and for evaluating the cerebral circulation in occlusive disease of the carotid and vertebral arteries.
Journal ArticleDOI
The nitrous oxide method for the quantitative determination of cerebral blood flow in man: theory, procedure and normal values
Seymour S. Kety,Carl F. Schmidt +1 more
TL;DR: The present report constitutes a description of the technique as it has now employed it in over 300 determinations, an examination of its underlying theory and validity, and values obtained with its use in 34 studies on 14 normal young men.
Journal ArticleDOI
Cerebral blood flow and oxygen consumption in man.
TL;DR: In the present study great emphasis will be put on information regarding cerebral oxygen consumption in man, whereas only scant attention will be paid to the intermediary metabolism of the brain.
Journal ArticleDOI
Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography
Robert J. Adams,Virgil McKie,Lewis L. Hsu,B Files,Elliott Vichinsky,Charles H. Pegelow,Miguel R. Abboud,Dianne Gallagher,Abdullah Kutlar,Fenwick T. Nichols,Duane Bonds,Donald Brambilla +11 more
TL;DR: Transfusion greatly reduces the risk of a first stroke in children with sickle cell anemia who have abnormal results on transcranial Doppler ultrasonography.
Journal ArticleDOI
Cerebral autoregulation dynamics in humans.
TL;DR: There was a highly significant inverse relation between rate of regulation and PaCO2 (p less than 0.001), indicating that the response rate of cerebral autoregulation in awake normal humans is profoundly dependent on vascular tone.
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