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Journal ArticleDOI

Vaccines targeting angiogenesis in melanoma

TLDR
In this paper, a review of the potential progress in developing vaccines for targeting melanoma angiogenesis in melanoma is presented, including DNA, peptide, protein, dendritic cell-based, and endothelial cell vaccines.
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This article is published in European Journal of Pharmacology.The article was published on 2021-12-05. It has received 3 citations till now. The article focuses on the topics: Angiogenesis & Melanoma.

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Citations
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Journal ArticleDOI

Statins and angiogenesis in non-cardiovascular diseases.

TL;DR: Statins inhibit HMG-CoA reductase by competitively inhibiting the active site of the enzyme, thus preventing cholesterol synthesis and reducing the risk of developing cardiovascular disease as mentioned in this paper .
Journal ArticleDOI

Application of VEGF/VEGFR peptide vaccines in cancer: a systematic review of clinical trials.

TL;DR: In this article , a systematic review was conducted to provide a comprehensive evaluation of the therapeutic efficacy, immune response, survival rate, and side effects of VEGF/VEGF receptor-based peptide vaccines.
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Nanoliposomal VEGF-R2 peptide vaccine acts as an effective therapeutic vaccine in a murine B16F10 model of melanoma

TL;DR: In this article , the VEGFR-2-derived peptides were restricted to both mouse MHC I and human HLA-A* using immunoinformatic tools and selected three peptides representing the highest binding affinities.
References
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Journal ArticleDOI

Dendritic cells and the control of immunity

TL;DR: Once a neglected cell type, dendritic cells can now be readily obtained in sufficient quantities to allow molecular and cell biological analysis and the realization that these cells are a powerful tool for manipulating the immune system is realized.
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Recent advances with liposomes as pharmaceutical carriers.

TL;DR: For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.
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Molecular mechanisms and clinical applications of angiogenesis

TL;DR: Preclinical and clinical studies have shown new molecular targets and principles, which may provide avenues for improving the therapeutic benefit from anti-angiogenic strategies.
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Mechanisms of angiogenesis and arteriogenesis.

TL;DR: The cellular and molecular mechanisms underlying the formation of endothelium-lined channels and their maturation via recruitment of smooth muscle cells (arteriogenesis) during physiological and pathological conditions are summarized, alongside with possible therapeutic applications.
Journal ArticleDOI

Vascular endothelial growth factor: basic science and clinical progress.

TL;DR: Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and an angiogenic inducer in a variety of in vivo models and is implicated in intraocular neovascularization associated with diabetic retinopathy and age-related macular degeneration.
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