Ventral and Dorsal Striatum Networks in Obesity: Link to Food Craving and Weight Gain.
Oren Contreras-Rodríguez,Cristina Martín-Pérez,Raquel Vilar-López,Antonio Verdejo-García,Antonio Verdejo-García +4 more
TLDR
Obesity is linked to alterations in the functional connectivity of dorsal striatal networks relevant to food craving and weight gain, which are associated with habit learning and thus compatible with the food addiction model of obesity.About:
This article is published in Biological Psychiatry.The article was published on 2017-05-01 and is currently open access. It has received 99 citations till now. The article focuses on the topics: Ventral striatum & Food craving.read more
Citations
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Journal ArticleDOI
The neurobiology of "food addiction" and its implications for obesity treatment and policy
Adrian Carter,Adrian Carter,Joshua Hendrikse,Natalia Lee,Murat Yücel,Antonio Verdejo-García,Zane B. Andrews,Wayne Hall +7 more
TL;DR: It is argued that the use of food addiction as a diagnostic category is premature and the potential positive and negative clinical, social, and public policy implications of describing obesity as a food addiction that require further investigation.
Journal ArticleDOI
Uncontrolled eating: a unifying heritable trait linked with obesity, overeating, personality and the brain
TL;DR: Treating different eating‐related constructs as a single concept, uncontrolled eating, enables drawing robust conclusions on the relationship between food intake and BMI, psychological variables and brain structure and function.
Journal ArticleDOI
Striatal dopamine regulates systemic glucose metabolism in humans and mice
Kasper W. ter Horst,Nicolette M. Lammers,Richard Trinko,Darren M. Opland,Martijn Figee,Mariëtte T. Ackermans,Jan Booij,Pepijn van den Munckhof,P. Richard Schuurman,Eric Fliers,Damiaan Denys,Ralph J. DiLeone,Susanne E. la Fleur,Susanne E. la Fleur,Mireille J. Serlie +14 more
TL;DR: The hypothesis that striatal neuronal activity regulates systemic glucose metabolism is supported, as a series of experiments supporting the regulation of peripheral glucose metabolism by striatal dopamine signaling are presented.
Journal ArticleDOI
Coordinated Ramping of Dorsal Striatal Pathways preceding Food Approach and Consumption.
Tanisha D London,Julia A. Licholai,Ilona Szczot,Mohamed A. Ali,Kimberly H. LeBlanc,Wambura C. Fobbs,Alexxai V. Kravitz +6 more
TL;DR: Dorsal striatal neurons exhibited long ramps in activity that preceded actions by several seconds, and may reflect upcoming actions, which may lead to improved therapies for disorders, such as drug addiction or obesity.
Book ChapterDOI
Psychological and Neurobiological Correlates of Food Addiction.
TL;DR: In this article, neuroimaging studies in response to food cues and the consumption of highly palatable foods in individuals with food addiction compared to healthy controls have shown differing activation patterns and connectivity in brain reward circuits including regions such as the striatum, amygdala, orbitofrontal cortex, insula, and nucleus accumbens.
References
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Region of interest analysis using an SPM toolbox
TL;DR: A toolbox called MarsBar is implemented for region of interest analysis within the SPM99 software package, which may have many advantages in terms of statistical power and the ease of interpretation of neuroimaging data.
Commentary A default mode of brain function: A brief history of an evolving idea
TL;DR: The concept of a default mode of brain function arose out of a focused need to explain the appearance of activity decreases in functional neuroimaging data when the control state was passive visual fixation or eyes closed resting as discussed by the authors.
Journal ArticleDOI
A default mode of brain function: a brief history of an evolving idea.
TL;DR: This work determined that activity decreases in functional neuroimaging data did not arise from activations in the resting state, and thereby implied the existence of a default mode of brain function.