Journal ArticleDOI
Walsh code based numerical mapping method for the identification of protein coding regions in eukaryotes
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TLDR
A new numerical mapping method based on Walsh codes is proposed to detect the coding regions in eukaryotes and is efficient as it attains 94 % accuracy, 85 % sensitivity and 96 % specificity when tested on the benchmark C. Elegans gene sequence.About:
This article is published in Biomedical Signal Processing and Control.The article was published on 2020-04-01. It has received 15 citations till now. The article focuses on the topics: Hadamard code.read more
Citations
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Journal ArticleDOI
A new numerical approach for DNA representation using modified Gabor wavelet transform for the identification of protein coding regions
TL;DR: Performance metrics indicate that the proposed encoding method exhibits relatively better performance than other numerical encoding methods.
Journal ArticleDOI
Gene prediction by the noise-assisted MEMD and wavelet transform for identifying the protein coding regions
TL;DR: A method on basis of the noise-assisted multivariate empirical mode decomposition (NA-MEMD) and the modified Gabor-wavelet transform (MGWT) that can enhance the spectra of the analyzed sequences, and improve the robustness of MGWT to different DNA sequences, thus obtaining higher identification accuracies of protein coding regions over other applied methods.
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Detection of exon location in eukaryotic DNA using a fuzzy adaptive Gabor wavelet transform
TL;DR: The proposed approach has an immense plus point of being capable of isolating detailed sub-regions in each exon efficiently proving its efficacy comparing with existing techniques.
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Study of effectiveness of FIR and IIR filters in Exon identification: A comparative approach
Subhajit Kar,Madhabi Ganguly +1 more
TL;DR: In this paper , DNA nucleotide sequence is converted into corresponding EIIP sequence in the first step and the sequence is passed through overall six FIR and IIR filters separately to extract the period three frequency components.
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DNA numerical encoding schemes for exon prediction: a recent history.
TL;DR: In this paper, a review of existing encoding (mapping) schemes was devised for the exon detection accuracy, and a comparative analysis was formulated to emphasize the importance of the genetic code setting of amino acids considered for application related to computational elucidation for exon Detection.
References
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An introduction to ROC analysis
TL;DR: The purpose of this article is to serve as an introduction to ROC graphs and as a guide for using them in research.
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Evolution of long-range fractal correlations and 1/f noise in DNA base sequences.
TL;DR: Spectral density measurements of individual base positions demonstrate the ubiquity of low-frequency 1/f β noise and long-range fractal correlations as well as prominent short-range periodicities.
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Genomic signal processing
TL;DR: Digital signal processing provides a set of novel and useful tools for solving highly relevant problems in genomic information science and technology, in the form of local texture, color spectrograms visually provide significant information about biomolecular sequences which facilitates understanding of local nature, structure, and function.
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ACE-inhibition induces a cardioprotective transcriptional response in the metabolic syndrome heart
Aziza Yakubova,Lieven Thorrez,Dmitry Svetlichnyy,Liesbeth Zwarts,Veerle Vulsteke,Griet Laenen,Wouter Oosterlinck,Yves Moreau,Luc Dehaspe,Jeroen Van Houdt,Álvaro Cortés-Calabuig,Bart De Moor,Patrick Callaerts,Paul Herijgers +13 more
TL;DR: It is concluded that MetS and control murine hearts have unique transcriptional profiles and exhibit a partially specific transcriptional response to ACE-inhibition, which appears to counteract some of the MetS-specific pathways, while also activating cardioprotective mechanisms.
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Frequency-domain analysis of biomolecular sequences
TL;DR: An optimization procedure improving upon traditional Fourier analysis performance in distinguishing coding from noncoding regions in DNA sequences is provided and it is demonstrated that color spectrograms can visually provide significant information about biomolecular sequences, thus facilitating understanding of local nature, structure and function.