Open Access
What is meant by intention to treat analysis? Survey of published randomised controlled trials
TLDR
To assess the methodological quality of intention to treat analysis as reported in randomised controlled trials in four large medical journals, a design survey of all reports of randomisation published in 1997 in the BMJ, Lancet, JAMA, and JAMA is conducted.Abstract:
Objectives To assess the methodological quality of intention to treat analysis as reported in randomised controlled trials in four large medical journals. Design Survey of all reports of randomised controlled trials published in 1997 in the BMJ,Lancet, JAMA, andread more
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Chapter 8: Assessing risk of bias in included studies
TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions (ISBN 978-0470057964) is published by John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex PO19 8SQ, England.
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Assessing Risk of Bias in Included Studies
TL;DR: In this paper, the authors propose a new algorithm called 1.8.1.1-2.0-1.8-1/2.8/1/1.
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CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials.
TL;DR: The CONSORT (Consolidated Standards of Reporting Trials) statement as discussed by the authors is used worldwide to improve the reporting of randomized, controlled trials. Schulz and colleagues describe the latest version, CONSORT 2010, which updates the reporting guideline based on new methodological evidence and accumulating experience.
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Standards of Evidence: Criteria for Efficacy, Effectiveness and Dissemination
Brian R. Flay,Anthony Biglan,Robert F. Boruch,Felipe González Castro,Denise C. Gottfredson,Sheppard G. Kellam,Eve K. Mościcki,Steven P. Schinke,Jeffrey C. Valentine,Peter Ji +9 more
TL;DR: These Standards will inform efforts in the field to find prevention Programs and policies that are of proven efficacy, effectiveness, or readiness for adoption and will guide prevention scientists as they seek to discover, research, and bring to the field new prevention programs and policies.
References
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Statistical Analysis with Missing Data
TL;DR: This work states that maximum Likelihood for General Patterns of Missing Data: Introduction and Theory with Ignorable Nonresponse and large-Sample Inference Based on Maximum Likelihood Estimates is likely to be high.
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Users' Guides to the Medical Literature
Gordon H. Guyatt,Drummond Rennie +1 more
TL;DR: Without a way of critically appraising the information they receive, clinicians are relatively helpless in deciding what new information to learn and decide how to modify their practice.
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Improving the quality of reporting of randomized controlled trials. The CONSORT statement.
Colin B. Begg,Mildred K. Cho,Susan Eastwood,Richard Horton,David Moher,Ingram Olkin,Roy M. Pitkin,Drummond Rennie,Kenneth F. Schulz,David L. Simel,Donna F. Stroup +10 more
TL;DR: For RCTs to ultimately benefit patients, the published report should be of the highest possible standard and should provide the reader with the ability to make informed judgments regarding the internal and external validity of the trial.
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The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenous-vein coronary-artery bypass grafts.
TL;DR: Aggressive lowering of LDL cholesterol levels to below 100 mg per deciliter reduced the progression of atherosclerosis in grafts and low-dose warfarin did not reduce the progression in patients with aortocoronary bypass grafts.
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