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These findings suggest that dietary amino acids can directly affect molecular signaling in skeletal muscle, further indicating that dietary manipulation with specific amino acids could potentially attenuate muscle loss with dietary protein deficiency.
Since it is known that amino acid supplementation stimulates the transport of amino acids into the skeletal muscles, and administration of exogenous amino acids after exercise increases protein synthesis while reducing protein breakdown, it is plausible that amino acid supplementation is effective for reducing muscle damage and / or enhancing recovery from muscle damage.
Nutritional supplementation has been investigated to offset the severe loss of protein, and recent evidence suggests that diets enriched in branched‐chain amino acids (BCAAs) may be especially beneficial.
Because active skeletal muscle is likely the principal consumer of these amino acids, the data suggest that gut protein-derived amino acids are utilized for the attenuation of net muscle protein catabolism during and immediately following exercise.
Weight loss followed by weight maintenance leads to differential changes in amino acid levels associated with obesity.
show that, rather than having a direct toxic effect, dietary branched-chain amino acids (BCAAs) appear to induce hyperphagia, owing to an imbalance between BCAAs and other amino acids, which reduces lifespan as a consequence of obesity.
Crystalline amino acids can be used to improve amino acid balance and reduce excessive intake of protein which should improve feed efficiency.
Our findings underscore the potential importance of dietary interventions in improving amino acid profiles (i. e., reducing diabetes risk-enhancing amino acid concentrations) along with and beyond weight loss.
Branched chain amino acids are good candidates for supplemental nutrients for both obese and non-obese LC patients.
A reliable and inexpensive method for the measurement of proteinogenic amino acids was developed.