J
Jibran A Wali
Researcher at University of Sydney
Publications - 27
Citations - 961
Jibran A Wali is an academic researcher from University of Sydney. The author has contributed to research in topics: Insulin resistance & Adipose tissue. The author has an hindex of 12, co-authored 26 publications receiving 549 citations. Previous affiliations of Jibran A Wali include University of Melbourne & St. Vincent's Institute of Medical Research.
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Journal ArticleDOI
Branched chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control.
Samantha M. Solon-Biet,Victoria C. Cogger,Tamara Pulpitel,Devin Wahl,Devin Wahl,Ximonie Clark,Elena E. Bagley,Gabrielle C. Gregoriou,Alistair M. Senior,Qiao-Ping Wang,Qiao-Ping Wang,Amanda E. Brandon,Ruth Perks,John F. O'Sullivan,Yen Chin Koay,Kim S. Bell-Anderson,Melkam A. Kebede,Belinda Yau,Clare Atkinson,Gunbjørg Svineng,Timothy Dodgson,Jibran A Wali,Matthew D.W. Piper,Paula Juricic,Linda Partridge,Adam J. Rose,David Raubenheimer,Gregory J. Cooney,David G. Le Couteur,Stephen J. Simpson +29 more
TL;DR: It is shown that when dietary BCAAs are varied against a fixed, isocaloric macronutrient background, long-term exposure to high BCAA diets leads to hyperphagia, obesity and reduced lifespan, which reduces lifespan as a consequence of obesity.
Journal ArticleDOI
Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework
Samantha M. Solon-Biet,Victoria C. Cogger,Tamara Pulpitel,Marika Heblinski,Devin Wahl,Aisling C. McMahon,Alessandra Warren,Jessica Durrant-Whyte,Kirsty A Walters,Kirsty A Walters,James R. Krycer,Fleur Ponton,Fleur Ponton,Rahul Gokarn,Jibran A Wali,Kari Ruohonen,Arthur D. Conigrave,David E. James,David Raubenheimer,Christopher D. Morrison,David G. Le Couteur,Stephen J. Simpson +21 more
TL;DR: The Geometric Framework, a nutritional modeling platform, is used to help reconcile apparently conflicting findings in mice confined to one of 25 diets that varied in protein, carbohydrate, and fat content, and show that FGF21 was elevated under low protein intakes and maximally when low protein was coupled with high carbohydrate intakes.
Journal ArticleDOI
Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice.
Devin Wahl,Samantha M. Solon-Biet,Qiao-Ping Wang,Qiao-Ping Wang,Jibran A Wali,Tamara Pulpitel,Ximonie Clark,David Raubenheimer,Alistair M. Senior,David A. Sinclair,David A. Sinclair,Gregory J. Cooney,Rafael de Cabo,Victoria C. Cogger,Stephen J. Simpson,David G. Le Couteur +15 more
TL;DR: Calorie restriction and ad libitum low-protein, high-carbohydrate diets improve cardiometabolic health in mice and positively affect hippocampus biology in mice by influencing hippocampus gene expression, nutrient-sensing pathways, dendritic morphology, and cognition.
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Cardio-Metabolic Effects of High-Fat Diets and Their Underlying Mechanisms-A Narrative Review.
Jibran A Wali,Natalia Jarzebska,David Raubenheimer,Stephen J. Simpson,Roman N. Rodionov,John F. O'Sullivan +5 more
TL;DR: It is indicated that healthy monounsaturated fats are more effective in preventing cardiovascular mortality and coronary artery disease than are low-fat, low-cholesterol diets and antioxidant and anti-inflammatory effects of Mediterranean diets are potential mediators of these benefits.
Journal ArticleDOI
Linking metabolic abnormalities to apoptotic pathways in Beta cells in type 2 diabetes.
TL;DR: Hyperglycaemia, hyperlipidaemia and islet amyloid poly-peptide (IAPP) represent important possible causes of increased beta-cell apoptosis and the link between upstream metabolic abnormalities and downstream apoptotic machinery is investigated.