What happens if you inject graphene oxide?
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| Papers (10) | Insight |
|---|---|
111 Citations | Besides, graphene oxide has a negative effect on the biological treatment. |
| The suitable introduction of graphene oxide could result in obvious enhancement on the efficiency. | |
| It is possible that graphene oxide can cause multigenerational harmful effects. | |
43 Citations | As discussed in this review, the literature suggests that a total characterization of graphene oxide must be conducted because oxidation debris (synthesis impurities) present in the graphene oxides could act as a graphene oxide surfactant, stabilizing aqueous dispersions. |
80 Citations | It reveals that graphene oxide layers could get better water permeability after reduction. |
| This strongly doped graphene is very different from "graphene oxide" made by mineral acid attack. | |
16 Citations | Characterizations indicate that graphene oxide is successfully reduced to graphene by sugar. |
30 Citations | The strong impact of the size of graphene oxide on the interaction between proteins and graphene oxide has been confirmed, as well. |
357 Citations | Graphene, graphene oxide, and reduced graphene oxide elicit toxic effects both in vitro and in vivo, whereas surface modifications can significantly reduce their toxic interactions with living systems. |
48 Citations | HIGHLIGHTSReduced Graphene Oxide & Graphene Oxide can cause potential environmental hazards. Mechanism of ocular toxicity of the materials is complex but not to be identified. Short‐term exposure tests indicate: Graphene Oxide has apparent ocular toxicity. |
Related Questions
How does graphene oxide affect the bacteria?5 answersGraphene oxide (GO) affects bacteria through multiple mechanisms. Firstly, GO can attach to the bacterial cell surface either in parallel or perpendicular interaction modes, depending on the surface oxygen content (SOC) of the GO. The interaction mode is related to the rigidity of the GO, with high SOC GO being more flexible and able to wrap bacteria, while lower SOC GO tends to contact bacteria with their edges. Secondly, GO can cause damage to the cellular ultrastructure of bacteria, with Ag-GO causing the most severe damage and GO causing intermediate damage. The damage is correlated with specific Fourier transform infrared spectroscopy (FTIR) spectral metrics, indicating disruption of the lipopolysaccharide, peptidoglycan, and phospholipid bilayers. Additionally, GO can decrease the ability of bacteria to form biofilms on surfaces, reducing biofilm formation on implantable medical devices. Finally, GO exhibits antimicrobial activity by inducing cellular damage, oxidative stress, and limiting physical movements and metabolism of bacteria.
What are the effects of graphene oxide on gap junction protein expression?5 answersGraphene oxide (GO) has been shown to have effects on the expression of gap junction proteins. In a study by Nakashima et al., it was found that the expression of the gap junction protein connexin (Cx) 32 decreased as hepatocellular carcinoma (HCC) progressed, suggesting a potential role of Cx32 in hepatocarcinogenesis. Another study by Rudnytska et al. demonstrated that GO treatment led to the up-regulation of key regulatory genes involved in cell proliferation, such as TOB1, HSPA5, EDEM1, MYBL1, and MYBL2, in normal human astrocytes. Ghazimoradi et al. reviewed the epigenetic alterations caused by GO, including changes in DNA methylation, histone modification, and altered expression of non-coding RNAs. Additionally, de Lázaro and Kostarelos found that exposure to GO resulted in significant deviations in the expression of various reference genes, including ribosomal proteins, which are crucial for appropriate qPCR data normalization. Overall, these studies suggest that GO can affect the expression of gap junction proteins and other regulatory genes, potentially impacting cellular processes and disease progression.
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