Showing papers on "Acetone published in 1971"
TL;DR: Acute oral toxicity studies in newborn rats, in 14-day olds, in young adult and in older adult rats to find the approximate doses inducing the first observable signs of toxic action and special evaluation was given to ethyl alcohol, methyl alcohol, benzene, and chloroform because of currently available documentation for these solvents.
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TL;DR: A new mechanism for the subterminal oxidation of methyl ketones by microorganisms is proposed whereby the first intermediate produced is an acetate ester which subsequently is cleaved to acetate and a primary alcohol two carbons shorter than the original ketone substrate.
102 citations
TL;DR: The enthalpy of mixing of dimethylsulfoxide and water has a minimum of −662 cal mol−1 at 0.35 moles fraction, and the enthalpies of mixing with the ketones are nearly symmetric in mole fraction as discussed by the authors.
74 citations
74 citations
TL;DR: If these effects of volatile anesthetics on erythrocyte membranes also occur on electrically excitable membranes, including nerve ending, then this phenomenon could explain how methanol, ethanol, propanol and acetone increase the frequency of miniature end-plate potentials, or how they sensitize muscles to acetylcholine.
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TL;DR: Aqueous solutions of 2-mercaptoethanol have been irradiated with pulses of 4 MeV electrons and with 240 kVp x-rays to isolate effects due to the various primary species and reaction products have been identified by gas chromatography and functional group analysis.
Abstract: SummaryAqueous solutions of 2-mercaptoethanol have been irradiated with pulses of 4 MeV electrons and with 240 kVp x-rays. The specific rate-constants for reactions of hydroxyl radicals, hydrated electrons and hydrogen atoms with the thiol were found to be 6·5 × 109, 1·2 × 1010 and 2 × 109 M−1 sec−1, respectively. Reaction products have been identified by gas chromatography and functional group analysis as hydrogen peroxide, hydrogen sulphide, acetaldehyde, ethanol and dithiodiglycol. Yields were determined quantitatively by spectrophotometric means after the addition, where necessary, of suitable reagents. Radical scavengers such as acetone have been used to isolate effects due to the various primary species. In the absence of oxygen, dithiodiglycol was formed with G up to 5 while hydrogen peroxide was formed in very small yield. In oxygenated solutions, dithiodiglycol and hydrogen peroxide were formed in equal yields with G values up to about 30, while hydrogen sulphide and ethanol had yields up to G ∼ ...
TL;DR: In this article, various metal oxides combined with molybdenum trioxide have been examined for their catalytic activities in the oxidation of propylene to acetone, and the results showed that the most effective catalysts, namely, SnO2MoO3 and Co3O4, showed high activity and selectivity for acetone formation in common with the corresponding poor catalysts.
TL;DR: In this paper, it was shown that the electron affinity of acetone is intermediate between those of naphthalene and anthracene, and that inorganic anions, e.g., CNS, are oxidized by both solvent cations and solvent triplet states.
Abstract: Pulse radiolysis experiments on acetone solutions have confirmed that G(triplet)= 1.0. In addition the yields G(singlet)= 0.34 and G(free ions)= 1.1 have been evaluated. It has been demonstrated that the electron affinity of acetone is intermediate between those of naphthalene and anthracene. Extinction coefficients of some aromatic hydrocarbon cations have been determined, and it has been shown that inorganic anions, e.g., CNS–, are oxidized by both solvent cations and solvent triplet states. Rate constants for the reaction of acetone triplet with various solutes have been determined by competition studies.
TL;DR: Integral heats of solution of NaBPh4 in the same aqueous binary solvents containing 20 % by volume (about 005 mol fraction) of cosolvent were also determined at 15, 25 and 35°C Corresponding excess partial molal heat capacities Δtextdecoration:overlineC°p were derived at 20 and 30°C.
Abstract: Integral heats of solution of Bu4NBr in aqueous binary solvent mixtures (containing 00 to 030 mol fraction of consolvent) of t-butanol, acetone, dioxan and ethylene glycol were determined at 15, 25, and 35°C Integral heats of solution of NaBPh4 in the same aqueous binary solvents containing 20 % by volume (about 005 mol fraction) of cosolvent were also determined at 15, 25 and 35°C Corresponding excess partial molal heat capacities Δtext-decoration:overlineC°p were derived at 20 and 30°C The partial molal enthalpies Δtext-decoration:overlineH°s of Bu4 NBr increased (sharply in aqueous t-butanol up to 006 mol fraction) with the addition of increasing amount of cosolvent to water till the maximum value was attained at 01–03 mol fraction of cosolvent The endothermicity maxima Δtext-decoration:overlineH°smax were in the decreasing order of t-butanol > acetone > ethylene glycol > dioxan text-decoration:overlineH°smax decreased with increasing temperatures in all aqueous binary solvents text-decoration:overlineC°p results indicate that addition of small amounts of t-butanol and acetone stabilize the water structure, the maximum stabilization occurring around 004 mol fraction of acetone and t-butanol Further addition of t-butanol to 006 mol fraction results in complete collapse of the water structure, whereas further addition of acetone results in gradual breakdown of the water structure which continues up to 03 mol fraction of acetone Dioxan and ethylene glycol seem to have net structure breaking influence on the water structure
Patent•
03 May 1971
TL;DR: In this paper, a decomposition of cumene hydroperoxide at temperatures in the range of from 65° to 105°C is described, using as decomposition catalyst sulfur dioxide or sulfuric acid in amount of between 0.002 and 0.5 percent by weight of water.
Abstract: In the process for obtaining phenol and acetone from cumene hydroperoxide which has been obtained by liquid-phase oxidation of cumene with molecular oxygen, dehydration of by-product dimethyl phenyl carbinol to form alpha-methylstyrene and formation of higher boiling by-products, such as alpha-methylstyrene dimers and cumyl phenol, are substantially reduced by an improvement which comprises, in combination: decomposing the cumene hydroperoxide at temperatures in the range of from 65° to 105° C. using as decomposition catalyst sulfur dioxide or sulfuric acid in amount of between 0.002 and 0.02 percent by weight of the cumene hydroperoxide feed, conducting the decomposition in the absence of added water in a decomposition mixture containing not more than about 0.5 percent by weight of water, and withdrawing decomposition product at cumene hydroperoxide concentrations not exceeding about 0.5 percent by weight to obtain a decomposition product containing principally phenol and acetone, then adding a base to the decomposition product in excess of amount required to neutralize the decomposition catalyst and sufficient to adjust the pH of the product to from about 5 to about 9, followed by fractional distillation to separate the decomposition product into an acetone fraction, a phenol fraction and one or more by-product fractions, so that dehydration of dimethyl phenyl carbinol and formation of higher boiling reaction products of alpha-methylstyrene are substantially avoided during the decomposition and fractional distillation steps.
TL;DR: The rate of drug release from tablets made with a methyl acrylate-methyl methacrylate copolymer matrix containing dispersed solid drug can be decreased by exposure to acetone vapor.
TL;DR: In this paper, a simple volatilization procedure was developed for the determination of residual acetone in oilseed meals and flours, where one gram of meal or flour and 0.2 g of water containing 0.4 mg of methanol were added into a 100 ml serum bottle, which was sealed and heated at 70 C for 5 hours in an oven.
Abstract: A simple volatilization procedure was developed for the determination of residual acetone in oilseed meals and flours. One gram of meal or flour and 0.2 g of water containing 0.4 mg of methanol are added into a 100 ml serum bottle, which is sealed and heated at 70 C for 5 hr in an oven. A 1 ml aliquot of the headspace gas is then analyzed by gas chromatography. The concentration of residual acetone is easily determined by comparing the ratio of the peak areas of acetone to methanol of the chromatogram with a calibration curve. Results are reproducible within ± 10%, and concentrations of a few ppm can be detected. This technique is much simpler and requires less operator time than other procedures available.
Patent•
02 Feb 1971
TL;DR: In this article, a process of bleaching carboxylic acid esters and/or epoxy compounds by irradiating the esters with ultraviolet light in the presence of ketone is described.
Abstract: A process of bleaching carboxylic acid esters and/or epoxy compounds by irradiating the esters and/or epoxy compounds with ultraviolet light in the presence of ketone. The preferred compounds bleached are the epoxidized higher fatty acid esters. Benzophenone, acetophenone, and acetone are examples of some suitable ketones.
Patent•
23 Feb 1971
TL;DR: In this paper, the authors define a derivative of DIPROPYLACETIC ACID called ((C3H7-)2-CH-COO-)2 -CA, which when mixed with a PHARMACEUTICALLY ACCEPTABLE CARRIER MEDIUM is used to increase the colicum content of the blood.
Abstract: A DERIVATIVE OF DIPROPYLACETIC ACID HAVING THE FORMULA: ((C3H7-)2-CH-COO-)2-CA WHICH WHEN MIXED WITH A PHARMACEUTICALLY ACCEPTABLE CARRIER MEDIUM IS ADMINISTERED TO HUMANS AND ANIMALS TO INCREASE THE CALCIUM CONTENT OF THE BLOOD, IS PREPARED BY STIRRING AND HEATING TO LESS THAN 10*C, A MIXTURE OF WATER AND CALCIUM OXIDE, ADDING DIPROPYLACETIC ACID, KEEPING THE MIXTURE FOR SEVERAL HOURS BELOW 100* C., FILTEING CONCENTRATING THE FILTRATE, TREATING THE FILTRATE WITH ACETONE, REMOVING THE ACETONE AND DRYING THE RESIDUE.
Patent•
08 Jun 1971TL;DR: In this article, a waste stream derived from the reaction of phenol and acetone in the presence of an acidic condensing agent can be treated with a molecular sieve to obtain good yields of the phenol in the effluent stream either in isolated form or as part of the compounds present in the waste stream.
Abstract: Bisphenol-A waste stream derived from the reaction of phenol and acetone in the presence of an acidic condensing agent can be treated with a molecular sieve to obtain good yields of phenol present in the effluent stream either in isolated form or as part of the compounds present in the waste stream.
TL;DR: The photocycloaddition of acetone to cyclooctene (COE) or 1,3-cyclooctadiene (COD) yields isomeric cis-and trans-oxetanes in good yields as discussed by the authors.
Abstract: The photocycloaddition of acetone to cyclooctene (COE) or 1,3-cyclooctadiene (COD) yields isomeric cis-and trans-oxetanes in good yields. Kinetic studies of these reactions reveal that the photoaddition of acetone to COE proceeds via the attack of the triplet acetone on the ground state COE, while the addition to COD probably occurs by the attack of the excited singlet acetone on the ground state COD.
TL;DR: The thin-layer chromatographic behavior of a number of metals on DEAE-cellulose and on microcrystalline cellulose, Avicel SF, has been surveyed in binary solvent mixtures containing H 2 SO 4 and an organic solvent as discussed by the authors.
TL;DR: In this article, the reactions with H2O2 of free radicals derived from 2-propanol, methanol, dimethoxymethane, and tetrahydrofuran were investigated.
Abstract: The reactions with H2O2 of free radicals derived from 2-propanol, methanol, dimethoxymethane, and tetrahydrofuran have been investigated by e.s.r. using in-cavity photolysis with acetone photosensi...