Adriano Arguedas

TL;DR: The data suggest that although 62% of children with severe ALRI are treated in hospitals, 81% of deaths happen outside hospitals, which suggests community-based management of severe disease could be an important complementary strategy to reduce pneumonia mortality and health inequities.

TL;DR: It is concluded that pediatric patients have a higher capacity for elimination of voriconazole per kilogram of body weight than do adult healthy volunteers and that dosages of 4 mg/kg may be required in children to achieve exposures consistent with those in adults following dosage of 3mg/kg.

TL;DR: An international group of multidisciplinary experts on middle-ear and paediatric infections met to explore where consensus exists on the management of acute otitis media and to propose to clinicians and public health officials their views on the actions needed to be taken to reduce the disease burden and the microbial antibiotic resistance.

TL;DR: It was found that high dose amoxicillin/clavulanate was highly efficacious in children with AOM, including those most likely to fail treatment, namely children <24 months of age and those with infections caused by PRSP.

TL;DR: It is demonstrated that the most common pneumococcal serotypes causing AOM globally are 3, 6A, 6B, 9V, 14, 19A, 19F, and 23F.