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Aida Sivro
Researcher at Centre for the AIDS Programme of Research in South Africa
Publications - 40
Citations - 805
Aida Sivro is an academic researcher from Centre for the AIDS Programme of Research in South Africa. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 8, co-authored 25 publications receiving 371 citations. Previous affiliations of Aida Sivro include University of Manitoba & University of KwaZulu-Natal.
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Journal ArticleDOI
Author Correction: Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection
Khadija Khan,Farina Karim,Yashica Ganga,Mallory Bernstein,Z. Jule,K S Reedoy,Sandile Cele,Gila Lustig,Daniel G. Amoako,Nicole Wolter,Natasha Samsunder,Aida Sivro,James Emmanuel San,Jennifer Giandhari,Houriiyah Tegally,Sureshnee Pillay,Yeshnee Naidoo,Matilda Mazibuko,Y. Miya,Nokuthula Ngcobo,Nithendra Manickchund,Nombulelo Magula,Quarraisha Abdool Karim,Anne von Gottberg,Salim S. Abdool Karim,W. Hanekom,Bernadett I Gosnell,Thandeka Theresa Emily Khoza Smit Wong,Thandeka. Khoza,Theresa Smit,Emily B. Wong,Richard J Lessells,Tulio de Oliveira,Mahomed Yunus S. Moosa,Alex Sigal +34 more
TL;DR: In this paper , the authors show that BA.4/BA.5 escape is similar to BA.1 in the absence or presence of previous vaccination as well as from vaccination without BA.5.
Journal ArticleDOI
Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women.
Lyle R. McKinnon,Lyle R. McKinnon,Lyle R. McKinnon,Lenine J. P. Liebenberg,Lenine J. P. Liebenberg,Nonhlanhla Yende-Zuma,Derseree Archary,Derseree Archary,Sinaye Ngcapu,Sinaye Ngcapu,Aida Sivro,Aida Sivro,Aida Sivro,Nico J. D. Nagelkerke,Jose Gerardo Garcia Lerma,Angela D. M. Kashuba,Lindi Masson,Lindi Masson,Leila E. Mansoor,Quarraisha Abdool Karim,Quarraisha Abdool Karim,Salim S. Abdool Karim,Salim S. Abdool Karim,Jo-Ann S. Passmore,Jo-Ann S. Passmore,Jo-Ann S. Passmore +25 more
TL;DR: A post hoc prospective analysis of results from the CAPRISA 004 trial for 1% tenofovir gel, one of the first trials to demonstrate protection against HIV infection, found that reducing genital inflammation in women may augment HIV prevention efforts.
Posted ContentDOI
Omicron sub-lineages BA.4/BA.5 escape BA.1 infection elicited neutralizing immunity
Khadija Khan,Faiz Karim,Yashica Ganga,Mallory Bernstein,Z. Jule,K S Reedoy,Sandile Cele,Gila Lustig,Daniel G. Amoako,Nicole Wolter,Natasha Samsunder,Aida Sivro,James Emmanuel San,Jennifer Giandhari,Houriiyah Tegally,Sureshnee Pillay,Yeshnee Naidoo,Matilda Mazibuko,Y. Miya,Ntombehle Ngcobo,Nithendra Manickchund,Nombulelo Magula,Quarraisha Abdool Karim,Anne von Gottberg,S. S. Abdool Karim,Willem A. Hanekom,Bernadett I Gosnell,COMMIT-KZN Team,Richard J Lessells,T. D. de Oliveira,Yumna Moosa,Alex Sigal +31 more
TL;DR: Low absolute neutralization levels for BA.4 and BA.5, particularly in the unvaccinated group, are unlikely to protect well against symptomatic infection, and may indicate that the SARS-CoV-2 Omicron sub-lineage has potential to result in a new infection wave.
Journal ArticleDOI
Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes
Aida Sivro,Aida Sivro,Alexandra Schuetz,Daniel J. Sheward,Vineet Joag,Sergey Yegorov,Lenine J. P. Liebenberg,Nonhlanhla Yende-Zuma,Andrew T. Stalker,Ruth S. Mwatelah,Philippe Selhorst,Nigel Garrett,Natasha Samsunder,Anisha Balgobin,Fatima Nawaz,Claudia Cicala,James Arthos,Anthony S. Fauci,AO Anzala,Joshua Kimani,Joshua Kimani,Bernard S. Bagaya,Bernard S. Bagaya,Noah Kiwanuka,Noah Kiwanuka,Carolyn Williamson,Carolyn Williamson,Rupert Kaul,Rupert Kaul,Jo-Ann S. Passmore,Jo-Ann S. Passmore,Nittaya Phanuphak,Jintanat Ananworanich,Jintanat Ananworanich,Aftab A. Ansari,Quarraisha Abdool Karim,Quarraisha Abdool Karim,Salim S. Abdool Karim,Salim S. Abdool Karim,Lyle R. McKinnon,Lyle R. McKinnon,Lyle R. McKinnon,Rv study groups +42 more
TL;DR: This study shows that pre-HIV infection frequencies of α4β7+ peripheral blood CD4+ T cells, independent of other T cell phenotypes and genital inflammation, were associated with increased rates of HIV acquisition in South African women and supported further evaluation of targeting α4 β7 integrin as a clinical intervention during HIV infection.
Journal ArticleDOI
A Functional Phenylacetic Acid Catabolic Pathway Is Required for Full Pathogenicity of Burkholderia cenocepacia in the Caenorhabditis elegans Host Model
Robyn J. Law,Jason N. R. Hamlin,Aida Sivro,Stuart J. McCorrister,Georgina A. Cardama,Silvia T. Cardona +5 more
TL;DR: These results demonstrate that B. cenocepacia possesses a functional PA degradation pathway and that the putative PA-CoA ring hydroxylation system is required for full pathogenicity in C. elegans.