A
Alberto Paradela
Researcher at Spanish National Research Council
Publications - 93
Citations - 2255
Alberto Paradela is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 26, co-authored 77 publications receiving 1891 citations. Previous affiliations of Alberto Paradela include University of Chile & Autonomous University of Madrid.
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Journal ArticleDOI
Advances in the analysis of protein phosphorylation.
TL;DR: This review aims at offering an overview at the most frequently used methods in phosphoprotein and phosphopeptide enrichment as well as on the most recent MS-based analysis strategies.
Journal ArticleDOI
Quantitative and qualitative influences of tapasin on the class I peptide repertoire
Anthony W. Purcell,Jeffrey J. Gorman,Marina García-Peydró,Alberto Paradela,Scott R. Burrows,Gert H. Talbo,Nihay Laham,Chen Au Peh,Eric C. Reynolds,José A. López de Castro,James McCluskey +10 more
TL;DR: Overall, the data reveal that tapasin quantitatively and qualitatively influences ligand selection by class I molecules.
Journal ArticleDOI
The SysteMHC Atlas project.
Wenguang Shao,Patrick G. A. Pedrioli,Witold Wolski,Cristian Scurtescu,Emanuel Schmid,Juan Antonio Vizcaíno,Mathieu Courcelles,Heiko Schuster,Daniel J. Kowalewski,Fabio Marino,Fabio Marino,Cecilia S. Lindestam Arlehamn,Kerrie Vaughan,Bjoern Peters,Alessandro Sette,Tom H. M. Ottenhoff,Krista E. Meijgaarden,Natalie E. Nieuwenhuizen,Stefan H. E. Kaufmann,Ralph Schlapbach,John C. Castle,Alexey I. Nesvizhskii,Morten Nielsen,Eric W. Deutsch,David S. Campbell,Robert L. Moritz,Roman A. Zubarev,Anders Jimmy Ytterberg,Anthony W. Purcell,Miguel Marcilla,Alberto Paradela,Qi Wang,Catherine E. Costello,Nicola Ternette,Peter A. van Veelen,Cécile A. C. M. van Els,Albert J. R. Heck,Gustavo A. de Souza,Gustavo A. de Souza,Ludvig M. Sollid,Arie Admon,Stefan Stevanovic,Hans-Georg Rammensee,Pierre Thibault,Claude Perreault,Michal Bassani-Sternberg,Ruedi Aebersold,Ruedi Aebersold,Etienne Caron +48 more
TL;DR: The SysteMHC Atlas disseminates quality controlled immunopeptidomic information to the public domain and serves as a community resource toward the generation of a high-quality comprehensive map of the human immunopePTidome and the support of consistent measurement of immunopeethidomic sample cohorts.
Journal ArticleDOI
Peptide rearrangement during quadrupole ion trap fragmentation: added complexity to MS/MS spectra.
Jesús Yagüe,Alberto Paradela,Manuel Ramos,Samuel Ogueta,Anabel Marina,Fernando Barahona,José A. López de Castro,Jesús Vázquez +7 more
TL;DR: The presence of anomalous fragments are described, which correspond to neutral loss elimination of internal amino acids from ions of the b series in quadrupole ion trap MS/MS spectra from naturally occurring peptides, which occurred preferentially with aliphatic amino acids.
Journal ArticleDOI
HLA-B27: a registry of constitutive peptide ligands.
J A López de Castro,Iñaki Alvarez,Miguel Marcilla,Alberto Paradela,M. Ramos,Laura Sesma,Manuel Vázquez +6 more
TL;DR: This analysis provides evidence that every peptide position, including "non-anchor" ones, may be subjected to selection on the basis of its contribution to HLA-B27 binding and also allows a quantization of residue preferences at known anchor positions.