A
Alessandra Zicari
Researcher at Sapienza University of Rome
Publications - 70
Citations - 1461
Alessandra Zicari is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Cytokine & Nitric oxide. The author has an hindex of 20, co-authored 66 publications receiving 1249 citations.
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Journal ArticleDOI
Synthesis and cytotoxicity of novel (thiazol-2-yl)hydrazine derivatives as promising anti-Candida agents.
Simone Carradori,Daniela Secci,Adriana Bolasco,Daniela Rivanera,Emanuela Mari,Alessandra Zicari,Lavinia Vittoria Lotti,Bruna Bizzarri +7 more
TL;DR: The concurrent presence of aliphatic chains or cycloaliphatic rings at N1-hydrazine and a 4-methyl/4-methoxyphenyl at C4 position of the thiazole nucleus exhibited an interesting anti-Candida inhibitory activity.
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Linked Activation of Nitric Oxide Synthase and Cyclooxygenase in Peripheral Monocytes of Asymptomatic Migraine Without Aura Patients
TL;DR: It is hypothesised that NOS and cyclooxygenase pathways in monocytes are linked and are, in MWA patients, up-regulated, even in a symptoms-free period, and NO and PGE2 hyperproduction could therefore be involved in the neurovascular modifications leading to migraine attacks.
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Graphene Oxide Nanoribbons Induce Autophagic Vacuoles in Neuroblastoma Cell Lines
Emanuela Mari,Stefania Mardente,Emanuela Morgante,Marco Tafani,Emanuela Lococo,Flavia Fico,Federica Valentini,Alessandra Zicari +7 more
TL;DR: G graphene oxide (GO) nanoribbons prepared by oxidative unzipping of single-wall carbon nanotubes and analyzed their toxicity in two human neuroblastoma cell lines suggest that the GO nanoparticle can be used for therapeutic delivery to the brain tissue with minimal effects on healthy cells.
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A novel class of selective anti-Helicobacter pylori agents 2-oxo-2H-chromene-3-carboxamide derivatives.
Franco Chimenti,Bruna Bizzarri,Adriana Bolasco,Daniela Secci,Paola Chimenti,Simone Carradori,Arianna Granese,Daniela Rivanera,D. Lilli,Alessandra Zicari,M.M. Scaltrito,Francesca Sisto +11 more
TL;DR: A novel class of selective anti-Helicobacter pylori agents, 2-oxo-2H-chromene-3-carboxamide derivatives, were prepared and evaluated for their anti-bacterial activity, showing little or no activity against different species of Gram-positive and Gram-negative bacteria and against various strains of pathogenic fungi.
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Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties
Daniela Secci,Simone Carradori,Bruna Bizzarri,Paola Chimenti,Celeste De Monte,Adriano Mollica,Daniela Rivanera,Alessandra Zicari,Emanuela Mari,Gokhan Zengin,Abdurrahman Aktumsek +10 more
TL;DR: Thirty-six new derivatives introducing aliphatic, cycloaliphatic and heteroaromatic moieties at N1-hydrazine connected with C2 position of the thiazolidinone nucleus are synthesized to characterize them as multi-target agents for fungal infections.