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Alexander E. Gorbalenya
Researcher at Moscow State University
Publications - 202
Citations - 35905
Alexander E. Gorbalenya is an academic researcher from Moscow State University. The author has contributed to research in topics: RNA & RNA-dependent RNA polymerase. The author has an hindex of 85, co-authored 198 publications receiving 30931 citations. Previous affiliations of Alexander E. Gorbalenya include Business International Corporation & Academy of Medical Sciences, United Kingdom.
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Journal ArticleDOI
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Sola,John Ziebuhr +16 more
TL;DR: The independent zoonotic transmission of SARS-CoV and SARS -CoV-2 highlights the need for studying viruses at the species level to complement research focused on individual pathogenic viruses of immediate significance.
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Helicases: amino acid sequence comparisons and structure-function relationships
TL;DR: Three large superfamilies and two smaller families of helicases are described and experimental results support the value of the conserved motifs for prediction of structure and function of the helicases.
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Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage.
Eric J. Snijder,Peter J. Bredenbeek,Jessika C. Dobbe,Volker Thiel,John Ziebuhr,Leo L.M. Poon,Yi Guan,Mikhail Rozanov,Willy J. M. Spaan,Alexander E. Gorbalenya +9 more
TL;DR: These newly recognized viral enzymes place the mechanism of coronavirus RNA synthesis in a completely new perspective and will be important targets for the design of antiviral strategies aimed at controlling the further spread of SARS-CoV.
Posted ContentDOI
Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group
Alexander E. Gorbalenya,Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Solá Gurpegui,John Ziebuhr +17 more
TL;DR: The Coronavirus Study Group (CSG) of the International Committee on Taxonomy of Viruses assessed the novelty of the human pathogen tentatively named 2019-nCoV and formally recognizes this virus as a sister to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
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Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group.
Raoul J. de Groot,Susan C. Baker,Ralph S. Baric,Caroline Brown,Christian Drosten,Luis Enjuanes,Ron A. M. Fouchier,Monica Galiano,Alexander E. Gorbalenya,Ziad A. Memish,Stanley Perlman,Leo L.M. Poon,Eric J. Snijder,Gwen Stephens,Patrick C. Y. Woo,Ali Moh Zaki,Maria Zambon,John Ziebuhr +17 more
TL;DR: During the summer of 2012, in Jeddah, Saudi Arabia, a hitherto unknown coronavirus was isolated from the sputum of a patient with acute pneumonia and renal failure and was provisionally called human coronav virus Erasmus Medical Center (EMC).