Amar H. Sheth

TL;DR: Cerebral palsy risk genes in enriched pathways were shown to regulate neuromotor function in a Drosophila reverse genetics screen, providing evidence for genetically mediated dysregulation of early neuronal connectivity in cerebral palsy.

TL;DR: This study expands previously described correlations between genomic drivers and clinical features, enhancing the understanding of meningioma pathogenesis, and laying further groundwork for the use of targeted therapies.

TL;DR: Different clinical outcomes and recurrence rates associated with meningioma molecular subgroups are described, emphasizing the importance of genomic characterization to guide post-operative management decisions for patients.

TL;DR: Exome-level insight is provided into Trigeminal neuralgia and genetically encoded impairment of GABA signaling and neuronal ion transport in TN pathogenesis is implicate.

TL;DR: In this paper, the authors assess microsatellite and KRAS status, prevalence, and impact on outcome in stage IV colorectal cancer (CRC) using multivariable Cox proportional hazards models.