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Amy S. Carlos
Researcher at Oregon Health & Science University
Publications - 11
Citations - 1608
Amy S. Carlos is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Gene & Population. The author has an hindex of 10, co-authored 10 publications receiving 1126 citations. Previous affiliations of Amy S. Carlos include Veterans Health Administration.
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Journal ArticleDOI
Functional genomic landscape of acute myeloid leukaemia
Jeffrey W. Tyner,Cristina E. Tognon,Cristina E. Tognon,Daniel Bottomly,Beth Wilmot,Stephen E. Kurtz,Samantha L. Savage,Nicola Long,Anna Reister Schultz,Elie Traer,Melissa L. Abel,Anupriya Agarwal,Aurora Blucher,Uma Borate,Jade Bryant,Russell T. Burke,Amy S. Carlos,Richie Carpenter,Joseph Carroll,Bill H. Chang,Cody Coblentz,Amanda d’Almeida,Rachel J. Cook,Alexey V. Danilov,Kim Hien T. Dao,Michie Degnin,Deirdre Devine,James Dibb,David K. Edwards,Christopher A. Eide,Christopher A. Eide,Isabel English,Jason M. Glover,Rachel Henson,Hibery Ho,Abdusebur Jemal,Kara Johnson,Ryan C. Johnson,Brian Junio,Andy Kaempf,Jessica Leonard,Chenwei Lin,Selina Qiuying Liu,Pierrette Lo,Marc M. Loriaux,Samuel B. Luty,Tara A. Macey,Jason D. MacManiman,Jacqueline Martinez,Motomi Mori,Dylan Nelson,Ceilidh Nichols,Jill Peters,Justin Ramsdill,Angela Rofelty,Robert Schuff,Robert P. Searles,Erik Segerdell,Rebecca Smith,Stephen E. Spurgeon,Tyler Sweeney,Aashis Thapa,Corinne Visser,Jake Wagner,Kevin Watanabe-Smith,Kristen Werth,Joelle Wolf,Libbey White,Amy Yates,Haijiao Zhang,Christopher R. Cogle,Robert H. Collins,Denise C. Connolly,Michael W. Deininger,Leylah Drusbosky,Christopher S. Hourigan,Craig T. Jordan,Patricia Kropf,Tara L. Lin,Micaela E. Martinez,Bruno C. Medeiros,Rachel R. Pallapati,Daniel A. Pollyea,Ronan T. Swords,Justin M. Watts,Scott Weir,David L. Wiest,Ryan M. Winters,Shannon K. McWeeney,Brian J. Druker,Brian J. Druker +90 more
TL;DR: Analyses of samples from patients with acute myeloid leukaemia reveal that drug response is associated with mutational status and gene expression; the generated dataset provides a basis for future clinical and functional studies of this disease.
Journal ArticleDOI
Regulation of Bone Mass in Mice by the Lipoxygenase Gene Alox15
Robert F. Klein,John Allard,Zafrira Avnur,Tania Nikolcheva,David Rotstein,Amy S. Carlos,Marie Shea,Ruth V. Waters,John K. Belknap,Gary Peltz,Eric S. Orwoll +10 more
TL;DR: Results suggest that drugs targeting the 12/15-lipoxygenase pathway merit investigation as a therapy for osteoporosis.
Journal ArticleDOI
Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms
Haijiao Zhang,Samantha L. Savage,Anna Reister Schultz,Daniel Bottomly,Libbey White,Erik Segerdell,Beth Wilmot,Shannon K. McWeeney,Christopher A. Eide,Christopher A. Eide,Tamilla Nechiporuk,Amy S. Carlos,Rachel Henson,Chenwei Lin,Robert P. Searles,Hoang Ho,Yee Ling Lam,Richard S. Sweat,Courtney Follit,Vinay K. Jain,Evan F. Lind,Gautam Borthakur,Guillermo Garcia-Manero,Farhad Ravandi,Hagop M. Kantarjian,Jorge E. Cortes,Robert H. Collins,Daelynn R. Buelow,Sharyn D. Baker,Brian J. Druker,Brian J. Druker,Jeffrey W. Tyner +31 more
TL;DR: Exome sequencing of samples from patients treated with the FLT3 inhibitor, crenolanib, is performed to show that resistance occurs due to diverse molecular mechanisms, not primarily due to secondaryFLT3 mutations.
Journal ArticleDOI
Ethanol inhibits human osteoblastic cell proliferation
TL;DR: A direct inhibitory effect of ethanol on osteoblast proliferation without overt cellular toxicity is confirmed that may, in part, explain the reduced bone mass observed in those who consume excessive amounts of alcohol.
Journal ArticleDOI
Mapping quantitative trait loci that influence femoral cross-sectional area in mice.
Robert F. Klein,Renn J. Turner,Lisa D. Skinner,Kristina Vartanian,Maqsood Serang,Amy S. Carlos,Marie Shea,John K. Belknap,Eric S. Orwoll +8 more
TL;DR: The genetic determinants of bone size appear to be largely, if not entirely, distinct from those that regulate BMD attainment, suggesting polygenic control of this trait.