E
Elie Traer
Researcher at Oregon Health & Science University
Publications - 82
Citations - 4698
Elie Traer is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Myeloid leukemia & Leukemia. The author has an hindex of 23, co-authored 69 publications receiving 3020 citations. Previous affiliations of Elie Traer include University of Utah & University of Texas Southwestern Medical Center.
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Journal ArticleDOI
Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML
Courtney D. DiNardo,Eytan M. Stein,S. de Botton,Gail J. Roboz,Jessica K. Altman,Alice S. Mims,Ronan T. Swords,Robert H. Collins,Gabriel N. Mannis,Daniel A. Pollyea,William B. Donnellan,Amir T. Fathi,A. Pigneux,Harry P. Erba,Gabrielle T. Prince,Anthony S. Stein,Geoffrey L. Uy,James M. Foran,Elie Traer,Robert K. Stuart,Martha Arellano,James L. Slack,Mikkael A. Sekeres,Christophe Willekens,Sung Choe,Hongfang Wang,Vickie Zhang,Katharine E. Yen,Stephanie M. Kapsalis,Hua Yang,David Dai,Bin Fan,Meredith Goldwasser,Hua Liu,Samuel V. Agresta,Bin Wu,Eyal C. Attar,Martin S. Tallman,Richard Stone,Hagop M. Kantarjian +39 more
TL;DR: In patients with advanced IDH1‐mutated relapsed or refractory AML, ivosidenib at a dose of 500 mg daily was associated with a low frequency of grade 3 or higher treatment‐related adverse events and with transfusion independence, durable remissions, and molecular remissions in some patients with complete remission.
Journal ArticleDOI
Functional genomic landscape of acute myeloid leukaemia
Jeffrey W. Tyner,Cristina E. Tognon,Cristina E. Tognon,Daniel Bottomly,Beth Wilmot,Stephen E. Kurtz,Samantha L. Savage,Nicola Long,Anna Reister Schultz,Elie Traer,Melissa L. Abel,Anupriya Agarwal,Aurora Blucher,Uma Borate,Jade Bryant,Russell T. Burke,Amy S. Carlos,Richie Carpenter,Joseph Carroll,Bill H. Chang,Cody Coblentz,Amanda d’Almeida,Rachel J. Cook,Alexey V. Danilov,Kim Hien T. Dao,Michie Degnin,Deirdre Devine,James Dibb,David K. Edwards,Christopher A. Eide,Christopher A. Eide,Isabel English,Jason M. Glover,Rachel Henson,Hibery Ho,Abdusebur Jemal,Kara Johnson,Ryan C. Johnson,Brian Junio,Andy Kaempf,Jessica Leonard,Chenwei Lin,Selina Qiuying Liu,Pierrette Lo,Marc M. Loriaux,Samuel B. Luty,Tara A. Macey,Jason D. MacManiman,Jacqueline Martinez,Motomi Mori,Dylan Nelson,Ceilidh Nichols,Jill Peters,Justin Ramsdill,Angela Rofelty,Robert Schuff,Robert P. Searles,Erik Segerdell,Rebecca Smith,Stephen E. Spurgeon,Tyler Sweeney,Aashis Thapa,Corinne Visser,Jake Wagner,Kevin Watanabe-Smith,Kristen Werth,Joelle Wolf,Libbey White,Amy Yates,Haijiao Zhang,Christopher R. Cogle,Robert H. Collins,Denise C. Connolly,Michael W. Deininger,Leylah Drusbosky,Christopher S. Hourigan,Craig T. Jordan,Patricia Kropf,Tara L. Lin,Micaela E. Martinez,Bruno C. Medeiros,Rachel R. Pallapati,Daniel A. Pollyea,Ronan T. Swords,Justin M. Watts,Scott Weir,David L. Wiest,Ryan M. Winters,Shannon K. McWeeney,Brian J. Druker,Brian J. Druker +90 more
TL;DR: Analyses of samples from patients with acute myeloid leukaemia reveal that drug response is associated with mutational status and gene expression; the generated dataset provides a basis for future clinical and functional studies of this disease.
Journal ArticleDOI
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
TL;DR: Biochemical analysis of an apoptotic response triggered by UV irradiation of HeLa cells revealed that the elimination of cytosolic inhibitors is required for mitochondrial release of cytochrome c and subsequent caspase activation.
Journal ArticleDOI
Proteogenomic Characterization of Endometrial Carcinoma.
Yongchao Dou,Emily Kawaler,Daniel Cui Zhou,Marina A. Gritsenko,Chen Huang,Lili Blumenberg,Alla Karpova,Vladislav A. Petyuk,Sara R. Savage,Shankha Satpathy,Wenke Liu,Yige Wu,Chia-Feng Tsai,Bo Wen,Zhi Li,Song Cao,Jamie Moon,Zhiao Shi,MacIntosh Cornwell,Matthew A. Wyczalkowski,Rosalie K. Chu,Suhas Vasaikar,Hua Zhou,Qingsong Gao,Ronald J. Moore,Kai Li,Sunantha Sethuraman,Matthew E. Monroe,Rui Zhao,David I. Heiman,Karsten Krug,Karl R. Clauser,Ramani Kothadia,Yosef E. Maruvka,Alexander R. Pico,Amanda E. Oliphant,Emily L. Hoskins,Samuel L. Pugh,Sean J.I. Beecroft,David W Adams,Jonathan C. Jarman,Andy T. Kong,Hui Yin Chang,Boris Reva,Yuxing Liao,Dmitry Rykunov,Antonio Colaprico,Xi Steven Chen,Andrzej Czekański,Marcin Jędryka,Rafal Matkowski,Maciej Wiznerowicz,Maciej Wiznerowicz,Tara Hiltke,Emily S. Boja,Christopher R. Kinsinger,Mehdi Mesri,Ana I. Robles,Henry Rodriguez,David G. Mutch,Katherine Fuh,Matthew J. Ellis,Deborah DeLair,Mathangi Thiagarajan,D. R. Mani,Gad Getz,Michael S. Noble,Alexey I. Nesvizhskii,Pei Wang,Matthew L. Anderson,Douglas A. Levine,Richard D. Smith,Samuel H. Payne,Kelly V. Ruggles,Karin D. Rodland,Karin D. Rodland,Li Ding,Bing Zhang,Tao Liu,David Fenyö,Anupriya Agarwal,Meenakshi Anurag,Dmitry M. Avtonomov,Chet Birger,Michael J. Birrer,Simina M. Boca,William Bocik,Uma Borate,Melissa Borucki,Meghan C. Burke,Shuang Cai,Anna Calinawan,Steven A. Carr,Sonya Carter,Patricia Castro,Sandra Cerda,Michelle Chaikin,Daniel W. Chan,Doug W. Chan,Alyssa Charamut,Feng Chen,Jin Chen,Lijun Chen,Lin Chen,David Chesla,Milan G. Chheda,Arul M. Chinnaiyan,Shrabanti Chowdhury,Marcin Cieslik,David J. Clark,Sandra Cottingham,Houston Culpepper,Jacob J. Day,Stephanie De Young,Emek Demir,Saravana M. Dhanasekaran,Rajiv Dhir,Marcin J. Domagalski,Peter Dottino,Brian J. Druker,Elizabeth R. Duffy,Maureen Dyer,Nathan Edwards,Robert Edwards,Kim Elburn,Jayson B. Field,Alicia Francis,Stacey Gabriel,Yifat Geffen,Daniel J. Geiszler,Michael A. Gillette,Andrew K. Godwin,Pamela Grady,Linda Hannick,Pushpa Hariharan,Sue Hilsenbeck,Barbara Hindenach,Katherine A. Hoadley,Runyu Hong,Galen Hostetter,James J. Hsieh,Yingwei Hu,Michael Ittmann,Eric J. Jaehnig,Scott D. Jewell,Jiayi Ji,Corbin D. Jones,Renee Karabon,Karen A. Ketchum,Munziba Khan,Beom-Jun Kim,Azra Krek,Tanya Krubit,Chandan Kumar-Sinha,Felipe D. Leprevost,Michael T. Lewis,Qing Kay Li,Yize Li,Hongwei Liu,Jan Lubinski,Weiping Ma,Rashna Madan,Ewa P. Malc,Anna Malovannaya,Sailaja Mareedu,Sanford P. Markey,Annette Marrero-Oliveras,John A. Martignetti,Jason E. McDermott,Peter B. McGarvey,John McGee,Piotr A. Mieczkowski,Francesmary Modugno,Rebecca I. Montgomery,Chelsea J. Newton,Gilbert S. Omenn,Amanda G. Paulovich,Amy M. Perou,Francesca Petralia,Paul D. Piehowski,Larisa Polonskaya,Liqun Qi,Shannon Richey,Karna Robinson,Nancy Roche,Daniel C. Rohrer,Eric E. Schadt,Michael Schnaubelt,Yan Shi,Tara Skelly,Lori J. Sokoll,Xiaoyu Song,Stephen E. Stein,James Suh,Donghui Tan,Darlene Tansil,Guo Ci Teo,Ratna R. Thangudu,Cristina E. Tognon,Elie Traer,Jeffrey W. Tyner,Ki Sung Um,Dana R. Valley,Negin Vatanian,Pankaj Vats,Uma Velvulou,Michael Vernon,Liang-Bo Wang,Ying Wang,Alex Webster,Thomas F. Westbrook,David C. Wheeler,Jeffrey R. Whiteaker,George D. Wilson,Yuriy Zakhartsev,Robert Zelt,Hui Zhang,Yuping Zhang,Zhen Zhang,Grace Zhao +219 more
TL;DR: A comprehensive proteogenomic characterization of endometrial carcinomas revealed possible new consequences of perturbations to the p53 and Wnt/β-catenin pathways, identified a potential role for circRNAs in the epithelial-mesenchymal transition, and provided new information about proteomic markers of clinical and genomic tumor subgroups, including relationships to known druggable pathways.
Journal ArticleDOI
Proteogenomic and metabolomic characterization of human glioblastoma
Liang-Bo Wang,Alla Karpova,Marina A. Gritsenko,Jennifer E. Kyle,Song Cao,Yize Li,Dmitry Rykunov,Antonio Colaprico,Antonio Colaprico,Joseph H. Rothstein,Runyu Hong,Vasileios Stathias,MacIntosh Cornwell,Francesca Petralia,Yige Wu,Boris Reva,Karsten Krug,Pietro Pugliese,Emily Kawaler,Lindsey K. Olsen,Wen-Wei Liang,Xiaoyu Song,Yongchao Dou,Michael C. Wendl,Wagma Caravan,Wenke Liu,Daniel Cui Zhou,Jiayi Ji,Chia-Feng Tsai,Vladislav A. Petyuk,Jamie Moon,Weiping Ma,Rosalie K. Chu,Karl K. Weitz,Ronald J. Moore,Matthew E. Monroe,Rui Zhao,Xiaolu Yang,Xiaolu Yang,Seungyeul Yoo,Azra Krek,Alexis Demopoulos,Houxiang Zhu,Matthew A. Wyczalkowski,Joshua F. McMichael,Brittany Henderson,Caleb M. Lindgren,Hannah Boekweg,Shuangjia Lu,Jessika Baral,Lijun Yao,Kelly L. Stratton,Lisa M. Bramer,Erika M. Zink,Sneha P. Couvillion,Kent J. Bloodsworth,Shankha Satpathy,Weiva Sieh,Simina M. Boca,Stephan C. Schürer,Feng Chen,Maciej Wiznerowicz,Maciej Wiznerowicz,Karen A. Ketchum,Emily S. Boja,Christopher R. Kinsinger,Ana I. Robles,Tara Hiltke,Mathangi Thiagarajan,Alexey I. Nesvizhskii,Bing Zhang,D. R. Mani,Michele Ceccarelli,Xi Chen,Xi Chen,Sandra Cottingham,Qing Kay Li,Albert H. Kim,David Fenyö,Kelly V. Ruggles,Henry Rodriguez,Mehdi Mesri,Samuel H. Payne,Adam C. Resnick,Pei Wang,Richard D. Smith,Antonio Iavarone,Milan G. Chheda,Jill S. Barnholtz-Sloan,Karin D. Rodland,Karin D. Rodland,Tao Liu,Li Ding,Anupriya Agarwal,Mitual Amin,Eunkyung An,Matthew L. Anderson,David W. Andrews,Thomas L. Bauer,Chet Birger,Michael J. Birrer,Lili Blumenberg,William Bocik,Uma Borate,Melissa Borucki,Meghan C. Burke,Shuang Cai,Anna Calinawan,Steven A. Carr,Sandra Cerda,Daniel W. Chan,Alyssa Charamut,Lin Chen,David Chesla,Arul M. Chinnaiyan,Shrabanti Chowdhury,Marcin Cieślik,David J. Clark,Houston Culpepper,Tomasz Czernicki,Fulvio D'Angelo,Jacob J. Day,Stephanie De Young,Emek Demir,Saravana M. Dhanasekaran,Rajiv Dhir,Marcin J. Domagalski,Brian J. Druker,Elizabeth R. Duffy,Maureen Dyer,Nathan Edwards,Robert Edwards,Kimberly Elburn,Matthew J. Ellis,Jennifer M. Eschbacher,Alicia Francis,Stacey Gabriel,Nikolay Gabrovski,Luciano Garofano,Gad Getz,Michael A. Gillette,Andrew K. Godwin,Denis A. Golbin,Ziad Hanhan,Linda Hannick,Pushpa Hariharan,Barbara Hindenach,Katherine A. Hoadley,Galen Hostetter,Chen Huang,Eric J. Jaehnig,Scott D. Jewell,Nan Ji,Corbin D. Jones,Alcida Karz,Wojciech Kaspera,Lyndon Kim,Ramani B. Kothadia,Chandan Kumar-Sinha,Jonathan T. Lei,Felipe D. Leprevost,Kai Li,Yuxing Liao,Jena Lilly,Hongwei Liu,Jan Lubinski,Rashna Madan,William W. Maggio,Ewa P. Malc,Anna Malovannaya,Sailaja Mareedu,Sanford P. Markey,Annette Marrero-Oliveras,Nina Martinez,Nicollette Maunganidze,Jason E. McDermott,Peter B. McGarvey,John McGee,Piotr A. Mieczkowski,Simona Migliozzi,Francesmary Modugno,Rebecca I. Montgomery,Chelsea J. Newton,Gilbert S. Omenn,Umut Ozbek,Oxana Paklina,Amanda G. Paulovich,Amy M. Perou,Alexander R. Pico,Paul D. Piehowski,Dimitris G. Placantonakis,Larisa Polonskaya,Olga Potapova,Barbara Pruetz,Liqun Qi,Shakti Ramkissoon,Adam C. Resnick,Shannon Richey,Gregory J. Riggins,Karna Robinson,Nancy Roche,Daniel C. Rohrer,Brian R. Rood,Larissa Rossell,Sara R. Savage,Eric E. Schadt,Yan Shi,Zhiao Shi,Yvonne Shutack,Shilpi Singh,Tara Skelly,Lori J. Sokoll,Jakub Stawicki,Stephen E. Stein,James Suh,Wojciech Szopa,Dave Tabor,Donghui Tan,Darlene Tansil,Ratna R. Thangudu,Cristina E. Tognon,Elie Traer,Shirley Tsang,Jeffrey W. Tyner,Ki Sung Um,Dana R. Valley,Suhas Vasaikar,Negin Vatanian,Uma Velvulou,Michael Vernon,Weiqing Wan,Junmei Wang,Alex Webster,Bo Wen,Jeffrey R. Whiteaker,George D. Wilson,Yuriy Zakhartsev,Robert Zelt,Hui Zhang,Liwei Zhang,Zhen Zhang,Grace Zhao,Jun Zhu +242 more
TL;DR: This article identified key phosphorylation events (e.g., phosphorylated PTPN11 and PLCG1) as potential switches mediating oncogenic pathway activation, as well as potential targets for EGFR-, TP53-, and RB1-altered tumors.