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Ana Reynders
Researcher at Aix-Marseille University
Publications - 22
Citations - 1361
Ana Reynders is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Medicine & Innate immune system. The author has an hindex of 8, co-authored 17 publications receiving 1131 citations. Previous affiliations of Ana Reynders include French Institute of Health and Medical Research & Centre national de la recherche scientifique.
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Journal ArticleDOI
Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin.
Carmelo Luci,Ana Reynders,Ivaylo I. Ivanov,Céline Cognet,Laurent Chiche,Lionel Chasson,Jean Hardwigsen,Esperanza Anguiano,Jacques Banchereau,Damien Chaussabel,Marc Dalod,Dan R. Littman,Eric Vivier,Elena Tomasello +13 more
TL;DR: The data show that lymphoid tissue–inducer cells and natural killer cells shared unanticipated similarities and emphasize the heterogeneity of NKp46+CD3− cells in innate immunity, lymphoid organization and local tissue repair.
Journal ArticleDOI
Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor
Emilie Narni-Mancinelli,Julie Chaix,Aurore Fenis,Yann M. Kerdiles,Nadia Yessaad,Ana Reynders,Claude Grégoire,Hervé Luche,Sophie Ugolini,Elena Tomasello,Thierry Walzer,Eric Vivier +11 more
TL;DR: F Fate mapping experiments demonstrated the stable expression of NKp46 on NK cells and allowed a reappraisal of the sequential steps of NK cell maturation, and genetic tracing showed that gut NKR+ROR-γt+ and NK cells represent two distinct lineages.
Journal ArticleDOI
Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells.
Ana Reynders,Ana Reynders,Nadia Yessaad,Nadia Yessaad,Thien-Phong Vu Manh,Thien-Phong Vu Manh,Marc Dalod,Marc Dalod,Aurore Fenis,Aurore Fenis,Camille Aubry,Camille Aubry,Camille Aubry,Georgios Nikitas,Georgios Nikitas,Bertrand Escalière,Bertrand Escalière,Jean-Christophe Renauld,Olivier Dussurget,Olivier Dussurget,Olivier Dussurget,Pascale Cossart,Pascale Cossart,Pascale Cossart,Marc Lecuit,Marc Lecuit,Marc Lecuit,Eric Vivier,Elena Tomasello,Elena Tomasello +29 more
TL;DR: It is demonstrated that small intestine (SI) NKp46+RORγt− ILCs correspond to SI NK cells and that the IL‐1β/IL‐1R1/MyD88 pathway, but not the commensal flora, drove IL‐22 production by NKp 46+rorγt+ I LCs, which is associated with subset‐specific transcriptional programmes and effector functions that govern their implication in gut innate immunity.
Journal ArticleDOI
TAFA4, a Chemokine-like Protein, Modulates Injury-Induced Mechanical and Chemical Pain Hypersensitivity in Mice
Marie-Claire Delfini,Annabelle Mantilleri,Stéphane Gaillard,Jizhe Hao,Ana Reynders,Pascale Malapert,Serge Alonso,Amaury François,Christian Barrère,Rebecca P. Seal,Marc Landry,Alain Eschallier,Abdelkrim Alloui,Emmanuel Bourinet,Patrick Delmas,Yves Le Feuvre,Aziz Moqrich +16 more
TL;DR: In wild-type C57/Bl6 mice, intrathecal administration of TAFA4 strongly reversed carrageenan-induced mechanical hypersensitivity, suggesting a potent analgesic role of TAfa4 in pain relief, and insights into how C-LTMR-derived TAFA 4 modulates neuronal excitability and controls the threshold of somatic sensation are provided.
Journal ArticleDOI
Transcriptional Profiling of Cutaneous MRGPRD Free Nerve Endings and C-LTMRs
Ana Reynders,Annabelle Mantilleri,Pascale Malapert,Stéphanie Rialle,Sabine Nidelet,Sophie Laffray,Corinne Beurrier,Emmanuel Bourinet,Aziz Moqrich +8 more
TL;DR: This study greatly expands the molecular characterization of C-LTMRs and suggests that this particular population of neurons shares some molecular features with Aβ and Aδ low-threshold mechanoreceptors.