J
Julie Chaix
Researcher at French Institute of Health and Medical Research
Publications - 14
Citations - 3181
Julie Chaix is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Lymphokine-activated killer cell & Interleukin 21. The author has an hindex of 11, co-authored 13 publications receiving 2845 citations. Previous affiliations of Julie Chaix include Centre national de la recherche scientifique & University of Pennsylvania.
Papers
More filters
Journal ArticleDOI
The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation
Scott M. Gordon,Julie Chaix,Levi J. Rupp,Junmin Wu,Sharline Madera,Joseph C. Sun,Tullia Lindsten,Steven L. Reiner +7 more
TL;DR: Two sequential, genetically separable checkpoints of NK cell maturation are revealed, the progression of which is metered largely by the anatomic localization of hematopoiesis.
Journal ArticleDOI
Maturation of mouse NK cells is a 4-stage developmental program.
Laura Chiossone,Julie Chaix,Julie Chaix,Nicolas Fuseri,Claude Roth,Eric Vivier,Thierry Walzer,Thierry Walzer +7 more
TL;DR: A 4-stage model ofNK-cell maturation appears to be associated with a progressive acquisition of NK-cell effector functions.
Journal ArticleDOI
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46
Thierry Walzer,Mathieu Blery,Julie Chaix,Nicolas Fuseri,Lionel Chasson,Scott H. Robbins,Sébastien Jaeger,Pascale Andre,Laurent Gauthier,Laurent Daniel,Karine Chemin,Yannis Morel,Marc Dalod,Jean Imbert,Michel Pierres,Alessandro Moretta,François Romagné,Eric Vivier +17 more
TL;DR: It is shown here thatNKp46 is expressed by NK cells in all mouse strains analyzed, as well as in three common monkey species, prompting a unifying phenotypic definition of NK cells across species based on NKp46 cell surface expression.
Journal ArticleDOI
Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor
Thierry Walzer,Laura Chiossone,Julie Chaix,Andrew R. Calver,Claude Carozzo,Claude Carozzo,Laure Garrigue-Antar,Laure Garrigue-Antar,Yannick Jacques,Yannick Jacques,Myriam Baratin,Elena Tomasello,Eric Vivier +12 more
TL;DR: It is found that S1P5 was required for the mobilization of NK cells to inflamed organs and the possibility that NK cell trafficking may be manipulated by therapies specifically targeting S1p5 is raised.
Journal ArticleDOI
Cutting Edge: Priming of NK Cells by IL-18
Julie Chaix,Marlowe S. Tessmer,Kasper Hoebe,Nicolas Fuseri,Bernhard Ryffel,Marc Dalod,Lena Alexopoulou,Bruce Beutler,Laurent Brossay,Eric Vivier,Thierry Walzer +10 more
TL;DR: It is demonstrated that IL-18 primes NK cells in vivo to produce IFN-γ upon subsequent stimulation with IL-12, and this suggests that priming byIL-18 leads to an improved translation of IFn-γ mRNA.