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Andreas F. Hottinger
Researcher at University of Lausanne
Publications - 111
Citations - 6173
Andreas F. Hottinger is an academic researcher from University of Lausanne. The author has contributed to research in topics: Temozolomide & Medicine. The author has an hindex of 29, co-authored 97 publications receiving 4774 citations. Previous affiliations of Andreas F. Hottinger include University Hospital of Lausanne & Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial
Roger Stupp,Roger Stupp,Roger Stupp,Sophie Taillibert,Sophie Taillibert,Andrew A. Kanner,William L. Read,William L. Read,David M. Steinberg,Benoit Lhermitte,Steven A. Toms,Ahmed Idbaih,Manmeet Ahluwalia,Karen Fink,Francesco Di Meco,Frank S. Lieberman,Jay-Jiguang Zhu,Jay-Jiguang Zhu,Giuseppe Stragliotto,David Tran,Steven Brem,Steven Brem,Andreas F. Hottinger,Eilon D. Kirson,Gitit Lavy-Shahaf,Uri Weinberg,Chae-Yong Kim,Sun Ha Paek,Garth Nicholas,Jordi Burna,H Hirte,Michael Weller,Yoram Palti,Monika E. Hegi,Zvi Ram +34 more
TL;DR: In the final analysis of this randomized clinical trial of patients with glioblastoma who had received standard radiochemotherapy, the addition of TTFields to maintenance temozolomide chemotherapy vs maintenance Temozolmide alone, resulted in statistically significant improvement in progression-free survival and overall survival.
Journal ArticleDOI
Maintenance therapy with tumor-Treating fields plus temozolomide vs temozolomide alone for glioblastoma a randomized clinical trial
Roger Stupp,Roger Stupp,S. Taillibert,Andrew A. Kanner,Santosh Kesari,David M. Steinberg,Steven A. Toms,Lynne P. Taylor,Frank S. Lieberman,Antonio Silvani,Karen Fink,Gene H. Barnett,Jay-Jiguang Zhu,John W. Henson,Herbert H. Engelhard,Thomas C. Chen,David Tran,Jan Sroubek,Nam D. Tran,Andreas F. Hottinger,Joseph Landolfi,Rajiv D. Desai,Manuela Caroli,Yvonne Kew,Jérôme Honnorat,Ahmed Idbaih,Eilon D. Kirson,Uri Weinberg,Yoram Palti,Monika E. Hegi,Zvi Ram +30 more
TL;DR: In this interim analysis of 315 patients with glioblastoma who had completed standard chemoradiation therapy, adding TTFields to maintenance temozolomide chemotherapy significantly prolonged progression-free and overall survival.
Journal ArticleDOI
Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma
Roger Stupp,Roger Stupp,Roger Stupp,S. Taillibert,S. Taillibert,Andrew A. Kanner,William L. Read,William L. Read,David M. Steinberg,Benoit Lhermitte,Steven A. Toms,Ahmed Idbaih,Manmeet Ahluwalia,Karen Fink,Francesco Di Meco,Frank S. Lieberman,Jay-Jiguang Zhu,Jay-Jiguang Zhu,Giuseppe Stragliotto,David Tran,Steven Brem,Andreas F. Hottinger,Eilon D. Kirson,Gitit Lavy-Shahaf,Uri Weinberg,Chae-Yong Kim,S. H. Paek,Garth Nicholas,Jordi Burna,Hal W. Hirte,Michael Weller,Yoram Palti,Monika E. Hegi,Zvi Ram +33 more
Journal ArticleDOI
Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology
Khê Hoang-Xuan,E M Bessell,Jacoline E C Bromberg,Andreas F. Hottinger,Matthias Preusser,Roberta Rudà,Uwe Schlegel,Tali Siegal,Carole Soussain,Carole Soussain,Ufuk Abacioglu,Nathalie Cassoux,Martina Deckert,Clemens M F Dirven,Andrés J.M. Ferreri,Francesc Graus,Roger Henriksson,Ulrich Herrlinger,Martin J.B. Taphoorn,Riccardo Soffietti,Michael Weller +20 more
TL;DR: These guidelines provide consensus considerations and recommendations for diagnosis, assessment, staging, and treatment of primary CNS lymphoma and should aid clinicians in their daily practice and decision making, and serve as a basis for future investigations in neuro-oncology.
Journal ArticleDOI
Complete and Long-Term Rescue of Lesioned Adult Motoneurons by Lentiviral-Mediated Expression of Glial Cell Line-Derived Neurotrophic Factor in the Facial Nucleus
TL;DR: This is the first evidence that viral-mediated delivery of GDNF close to the motoneuron cell bodies of the facial nucleus of adult mice can lead to complete and long-term protection against lesion-induced cell death.