Andrew Collins

TL;DR: It is found that rodent UV‐sensitive mutant cell lines of complementation groups 6 and 8 have wild‐type capacity for DNA repair as indicated by incision, cyclobutane pyrimidine dimer, and (6‐4) photoproduct removal, and ERCC6, the product of the gene defective in CS‐B and group 6 mutants, is implicated in the regulation of repair of actively transcribed genes in Cockaynesyndrome.

TL;DR: St retention of haplotype diversity in simulations that do not mirror genomic allele frequencies has no relevance to power for association mapping and favours a multi-stage design in which both models and density change adaptively.

TL;DR: High winter MDA levels are seen in those individuals with relatively low folic acid; they never occur in subjects with high plasma folic Acid, implying that folic acids might directly protect against lipid oxidation.

TL;DR: The potential problem of anomalous comets seen at the border of the gel, the so-called 'edge effects', has been addressed and a reliable, high throughput comet assay has applications in genotoxicity testing as well as ecogenotoxicology and human biomonitoring.

TL;DR: The hypothesis that antioxidants decrease genetic damage is supported, as well as the ferric reducing ability of plasma (a measure of total plasma antioxidant status) and the concentration of malondialdehyde as an indicator of oxidative stress.